About: Impact of phenotyping CYP2D6 in psychiatry     Goto   Sponge   NotDistinct   Permalink

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Description
  • Článek uvádí rozložení metabolického statusu u pacientů léčených paroxetinem. Srovnává vedl.účinky léčby a pomalý metabolický fenotyp. Rozdíl byl nalezen ve výskytu sex.dysfunkcí, který byl vyšší u pomalého fenotypu. (cs)
  • The paper deal with comparison of distribution therapeutic efficacy and side effects of long term paroxetine treatment within 50 patients genotyped and phenotyped to determine their metabolic status. No variation in therapeutic efficacy and common adverse effects between subjects classified as poor metabilisers and extensice metabolisers were found. A significantkly higher rate of sexual dysfunction was recored among patients with a PM Phenotype.
  • The paper deal with comparison of distribution therapeutic efficacy and side effects of long term paroxetine treatment within 50 patients genotyped and phenotyped to determine their metabolic status. No variation in therapeutic efficacy and common adverse effects between subjects classified as poor metabilisers and extensice metabolisers were found. A significantkly higher rate of sexual dysfunction was recored among patients with a PM Phenotype. (en)
Title
  • Impact of phenotyping CYP2D6 in psychiatry
  • Impact of phenotyping CYP2D6 in psychiatry (en)
  • Vliv fenotypizace CYP2D6 v psychiatrii (cs)
skos:prefLabel
  • Impact of phenotyping CYP2D6 in psychiatry
  • Impact of phenotyping CYP2D6 in psychiatry (en)
  • Vliv fenotypizace CYP2D6 v psychiatrii (cs)
skos:notation
  • RIV/00216224:14110/04:00010287!RIV08-MSM-14110___
http://linked.open.../vavai/riv/strany
  • 53-54
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM 141100001)
http://linked.open...iv/cisloPeriodika
  • suppl.4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 567388
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/04:00010287
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • phenotype; genotype; CYP2D6; clinical outcome (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [2E16EDF9CAA5]
http://linked.open...i/riv/nazevZdroje
  • Psychiatrie
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 8
http://linked.open...iv/tvurceVysledku
  • Kašpárek, Tomáš
  • Ravčuková, Barbora
  • Žourková, Alexandra
  • McCaskey Hadašová, Eva
  • Pulkrábková, Lucie
  • Robeš, Miroslav
http://linked.open...n/vavai/riv/zamer
issn
  • 1211-7579
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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