About: Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats     Goto   Sponge   NotDistinct   Permalink

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  • In the present study, modulation of the reinforcing effects of methamphetamine by the non-selective 5-HT2 receptor agonist alpha-methyl-serotonin was ascertained using the method of i.v. self-administration in rats. In summary, our findings suggest that 5-HT2 receptor activation might attenuate methamphetamine self-administration. These results are in accordance with the findings of Munzar et al. (1999) indicating that 5-HT mediation of discriminative stimulus actions of methamphetamine appears to be involved to a big extent in stimulation at 5-HT2A/2C receptors.
  • In the present study, modulation of the reinforcing effects of methamphetamine by the non-selective 5-HT2 receptor agonist alpha-methyl-serotonin was ascertained using the method of i.v. self-administration in rats. In summary, our findings suggest that 5-HT2 receptor activation might attenuate methamphetamine self-administration. These results are in accordance with the findings of Munzar et al. (1999) indicating that 5-HT mediation of discriminative stimulus actions of methamphetamine appears to be involved to a big extent in stimulation at 5-HT2A/2C receptors. (en)
  • In the present study, modulation of the reinforcing effects of methamphetamine by the non-selective 5-HT2 receptor agonist alpha-methyl-serotonin was ascertained using the method of i.v. self-administration in rats. In summary, our findings suggest that 5-HT2 receptor activation might attenuate methamphetamine self-administration. These results are in accordance with the findings of Munzar et al. (1999) indicating that 5-HT mediation of discriminative stimulus actions of methamphetamine appears to be involved to a big extent in stimulation at 5-HT2A/2C receptors. (cs)
Title
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats (en)
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats (cs)
skos:prefLabel
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats (en)
  • Pharmacological manipulation with 5-HT2 receptor subtype affects methamphetamine i.v. self-administration in rats (cs)
skos:notation
  • RIV/00216224:14110/03:00009236!RIV08-MSM-14110___
http://linked.open.../vavai/riv/strany
  • 205-205
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  • Z(MSM 141100001)
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  • 620750
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  • RIV/00216224:14110/03:00009236
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  • 5-HT2 receptor subtype; alpha-methyl-serotonin; methamphetamine; i.v. self-administration; rats (en)
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  • [25EC37A0827E]
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  • Prague, Czech Republic
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  • Prague (Czech Republic)
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  • Abstract Book of Sixth IBRO World Congress of Neuroscience
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http://linked.open...cetTvurcuVysledku
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  • Nováková, Jana
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
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  • Neuveden
https://schema.org/isbn
  • 80-239-0887-1
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  • 14110
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