| Attributes | Values |
|---|
| rdf:type
| |
| Description
| - Breast cancer is the most frequent malignancy in women in the world, with a cumulative lifetime risk estimated to be 10-12%. Cytogenic and molecular genetic analyses of breast tumor cells suggest that the development of human breast cancer involves the accumulation of alterations in genes which normally serve to control growth and differentiation. One type of this alteration is loss of heterozygosity (LOH), which is detected in many cases of breast cancer. LOH of tumor suppressor genes are associated with cancerogenesis. Several studies have indicated that the genes harbors on long arm of chromosome 11, could be detected during tumorogenesis. Deletions at 11q23 were detected in variety of human neoplasma, including breast. In this region can be harbor at least one tumor suppressor gene, which is inactivated during the establishment or progression of several types of tumors. Evidence for the existence of a tumor suppresor gene(s) in this region came from the observation that tumorgenicity of the MCF-7
- Breast cancer is the most frequent malignancy in women in the world, with a cumulative lifetime risk estimated to be 10-12%. Cytogenic and molecular genetic analyses of breast tumor cells suggest that the development of human breast cancer involves the accumulation of alterations in genes which normally serve to control growth and differentiation. One type of this alteration is loss of heterozygosity (LOH), which is detected in many cases of breast cancer. LOH of tumor suppressor genes are associated with cancerogenesis. Several studies have indicated that the genes harbors on long arm of chromosome 11, could be detected during tumorogenesis. Deletions at 11q23 were detected in variety of human neoplasma, including breast. In this region can be harbor at least one tumor suppressor gene, which is inactivated during the establishment or progression of several types of tumors. Evidence for the existence of a tumor suppresor gene(s) in this region came from the observation that tumorgenicity of the MCF-7 (en)
- Breast cancer is the most frequent malignancy in women in the world, with a cumulative lifetime risk estimated to be 10-12%. Cytogenic and molecular genetic analyses of breast tumor cells suggest that the development of human breast cancer involves the accumulation of alterations in genes which normally serve to control growth and differentiation. One type of this alteration is loss of heterozygosity (LOH), which is detected in many cases of breast cancer. LOH of tumor suppressor genes are associated with cancerogenesis. Several studies have indicated that the genes harbors on long arm of chromosome 11, could be detected during tumorogenesis. Deletions at 11q23 were detected in variety of human neoplasma, including breast. In this region can be harbor at least one tumor suppressor gene, which is inactivated during the establishment or progression of several types of tumors. Evidence for the existence of a tumor suppresor gene(s) in this region came from the observation that tumorgenicity of the MCF-7 (cs)
|
| Title
| - Dominant negative ATM mutationsn in breast cancer families
- Dominant negative ATM mutationsn in breast cancer families (en)
- Dominant negative ATM mutationsn in breast cancer families (cs)
|
| skos:prefLabel
| - Dominant negative ATM mutationsn in breast cancer families
- Dominant negative ATM mutationsn in breast cancer families (en)
- Dominant negative ATM mutationsn in breast cancer families (cs)
|
| skos:notation
| - RIV/00216224:14110/02:00007646!RIV08-MSM-14110___
|
| http://linked.open.../vavai/riv/strany
| |
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| |
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00007646
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| |
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Journal of the National Cancer Institute
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Vořechovský, Igor
- Lei, Haixin
- Lindblom, Arnica
- Strouhalová, Daria
|
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
| http://localhost/t...ganizacniJednotka
| |
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