About: Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e)

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K]e. In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K]e. (en) In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K]e. (cs)
Title	Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) (en) Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) (cs)
skos:prefLabel	Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) (en) Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e) (cs)
skos:notation	RIV/00216224:14110/02:00007142!RIV09-MSM-14110___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z2076919), Z(MSM 141100004)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Pásek, Michal Šimurda, Jiří
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	661314
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/02:00007142
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ventricular cell; low external [K]; tubular system; quantitative modelling (en)
http://linked.open.../riv/klicoveSlovo	tubular system quantitative modelling low external [K] ventricular cell
http://linked.open...ontrolniKodProRIV	[8CF5CDE812FB]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Brno University of Technology
http://linked.open...i/riv/nazevZdroje	Analysis of biomedical signals and images
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2002
http://linked.open...iv/tvurceVysledku	Pásek, Michal Šimurda, Jiří Christé, Georges
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open...ain/vavai/riv/wos	000178613000133
http://linked.open.../riv/zahajeniAkce	2002-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Dynamics of fluids, solids and their interactions http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20141100004
number of pages	3 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Vysoké učení technické v Brně. Nakladatelství VUTIUM
https://schema.org/isbn	80-214-2120-7
http://localhost/t...ganizacniJednotka	14110

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