| Attributes | Values |
|---|
| rdf:type
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| Description
| - The aim of the study was to focus on relationship among the associated genotype of G (8002) A and -3A/-4A endothelin-1 (ET-1) gene polymorphisms and some clinical and/ or biochemical parameters in the Czech (Caucasian) patients with chronic heart failure. 103 patients with chronic heart failure (functional class NYHA II-IV, ejection fraction <40%) were included into the study. The ET-1 gene polymorphisms were detected by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) methods. A significant decrease of the ET-1 associated genotype AG3A4A number (double heterozygote) was observed in CHF patients with plasma big-endothelin levels above 0.7 pmol/L compared to those with the levels below 0.7 pmol/L (OR=0.19, 95% confidential interval 0.06-0.57, P=0.005, Pcorr=0.03). We proved a significant decrease of the AG3A4A genotype number in the other groups compared to the group of patients with both big endothelin and endothelin-1 levels under 0.7 pmol/L (OR=0.22, 95% confide
- The aim of the study was to focus on relationship among the associated genotype of G (8002) A and -3A/-4A endothelin-1 (ET-1) gene polymorphisms and some clinical and/ or biochemical parameters in the Czech (Caucasian) patients with chronic heart failure. 103 patients with chronic heart failure (functional class NYHA II-IV, ejection fraction <40%) were included into the study. The ET-1 gene polymorphisms were detected by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) methods. A significant decrease of the ET-1 associated genotype AG3A4A number (double heterozygote) was observed in CHF patients with plasma big-endothelin levels above 0.7 pmol/L compared to those with the levels below 0.7 pmol/L (OR=0.19, 95% confidential interval 0.06-0.57, P=0.005, Pcorr=0.03). We proved a significant decrease of the AG3A4A genotype number in the other groups compared to the group of patients with both big endothelin and endothelin-1 levels under 0.7 pmol/L (OR=0.22, 95% confide (en)
- The aim of the study was to focus on relationship among the associated genotype of G (8002) A and -3A/-4A endothelin-1 (ET-1) gene polymorphisms and some clinical and/ or biochemical parameters in the Czech (Caucasian) patients with chronic heart failure. 103 patients with chronic heart failure (functional class NYHA II-IV, ejection fraction <40%) were included into the study. The ET-1 gene polymorphisms were detected by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) methods. A significant decrease of the ET-1 associated genotype AG3A4A number (double heterozygote) was observed in CHF patients with plasma big-endothelin levels above 0.7 pmol/L compared to those with the levels below 0.7 pmol/L (OR=0.19, 95% confidential interval 0.06-0.57, P=0.005, Pcorr=0.03). We proved a significant decrease of the AG3A4A genotype number in the other groups compared to the group of patients with both big endothelin and endothelin-1 levels under 0.7 pmol/L (OR=0.22, 95% confide (cs)
|
| Title
| - Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure
- Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure (en)
- Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure (cs)
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| skos:prefLabel
| - Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure
- Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure (en)
- Double heterozygote of two endothelin-1 gene polymorhisms (G8002A and -3A/-4A) is related to big endothelin levels in chronic heart failure (cs)
|
| skos:notation
| - RIV/00216224:14110/02:00005714!RIV09-GA0-14110___
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(GA306/96/0099), P(VS96097), Z(MSM 141100002)
|
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00005714
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - Endothelin gene; big endothelin and heart failure (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| - Experimental and Molecular Pathology
|
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Toman, Jiří
- Vašků, Anna
- Vítovec, Jiří
- Špinar, Jindřich
- Špinarová, Lenka
- Mužík, Jan
- Pávková Goldbergová, Monika
- Vácha, Jiří
|
| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
| http://localhost/t...ganizacniJednotka
| |
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