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| rdf:type
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| Description
| - Felbamate belongs to the antiepileptics of the third generation which are tested for their behavioural effects potentially useful particularly in depressive patients. The present study used the ethological model of agonistic behaviour based on the intra-species social conflict in male mice to investigate the effects of felbamate (15, 60 and 240 mg/kg, orally) on sociable, defensive-escape, aggressive and locomotor behaviour observed in singly-housed male mice during their social interactions with the non-aggressive group-housed male counterparts. In the aggressive mice felbamate produced a dose-dependent reduction in the behavioural score of aggressivity, significant after all doses tested. In the wide dosage interval of 15 - 240 mg/kg felbamate showed no sedative effect on locomotion, in addition, the ambulation was significantly disinhibited afte the dose of 15 mg/kg. The stimulatory effect of felbamate on locomotion was found also in the timid mice, significantly after the dose of 240 mg/kg, where
- Felbamate belongs to the antiepileptics of the third generation which are tested for their behavioural effects potentially useful particularly in depressive patients. The present study used the ethological model of agonistic behaviour based on the intra-species social conflict in male mice to investigate the effects of felbamate (15, 60 and 240 mg/kg, orally) on sociable, defensive-escape, aggressive and locomotor behaviour observed in singly-housed male mice during their social interactions with the non-aggressive group-housed male counterparts. In the aggressive mice felbamate produced a dose-dependent reduction in the behavioural score of aggressivity, significant after all doses tested. In the wide dosage interval of 15 - 240 mg/kg felbamate showed no sedative effect on locomotion, in addition, the ambulation was significantly disinhibited afte the dose of 15 mg/kg. The stimulatory effect of felbamate on locomotion was found also in the timid mice, significantly after the dose of 240 mg/kg, where (en)
- Felbamate belongs to the antiepileptics of the third generation which are tested for their behavioural effects potentially useful particularly in depressive patients. The present study used the ethological model of agonistic behaviour based on the intra-species social conflict in male mice to investigate the effects of felbamate (15, 60 and 240 mg/kg, orally) on sociable, defensive-escape, aggressive and locomotor behaviour observed in singly-housed male mice during their social interactions with the non-aggressive group-housed male counterparts. In the aggressive mice felbamate produced a dose-dependent reduction in the behavioural score of aggressivity, significant after all doses tested. In the wide dosage interval of 15 - 240 mg/kg felbamate showed no sedative effect on locomotion, in addition, the ambulation was significantly disinhibited afte the dose of 15 mg/kg. The stimulatory effect of felbamate on locomotion was found also in the timid mice, significantly after the dose of 240 mg/kg, where (cs)
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| Title
| - Behavioural effects of felbamate in the model of social interaction in mice
- Behavioural effects of felbamate in the model of social interaction in mice (en)
- Behavioural effects of felbamate in the model of social interaction in mice (cs)
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| skos:prefLabel
| - Behavioural effects of felbamate in the model of social interaction in mice
- Behavioural effects of felbamate in the model of social interaction in mice (en)
- Behavioural effects of felbamate in the model of social interaction in mice (cs)
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| skos:notation
| - RIV/00216224:14110/02:00005697!RIV08-MSM-14110___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00005697
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - animal behaviour; antidepressant; felbamate; mouse (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Šulcová, Alexandra
- Pistovčáková, Jana
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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