| Attributes | Values |
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| rdf:type
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| Description
| - Periodontal diseases belong to the most common chronic disorders affecting mankind. Smoking and impaired plasminogen activation with hypercoagulation and fibrinolysis inhibition have been proposed as having a role in predisposition to these diseases We investigated relationships among adult periodontitis, smoking and a variation in the deletion/insertion (4G/5G) promoter polymorphism of the plasminogen-activator-inhibitor-1 (PAI-1) gene in 304 Caucasian subjects. An association was detected between the deletion (4G) allele (and 4G/4G genotype) and periodontitis (p=0.0022, Pcorr.LT.0.01, p=0.014, Pcorr.LT.0.05). Even a stronger association occurred in non-smokers (p=0.00021, Pcorr.LT.0.01, p=0.0024, Pcorr.LT.0.05) where the presence of the PAI-1 gene 4G allele appears to be one of the risk factors for periodontitis.
- Periodontal diseases belong to the most common chronic disorders affecting mankind. Smoking and impaired plasminogen activation with hypercoagulation and fibrinolysis inhibition have been proposed as having a role in predisposition to these diseases We investigated relationships among adult periodontitis, smoking and a variation in the deletion/insertion (4G/5G) promoter polymorphism of the plasminogen-activator-inhibitor-1 (PAI-1) gene in 304 Caucasian subjects. An association was detected between the deletion (4G) allele (and 4G/4G genotype) and periodontitis (p=0.0022, Pcorr.LT.0.01, p=0.014, Pcorr.LT.0.05). Even a stronger association occurred in non-smokers (p=0.00021, Pcorr.LT.0.01, p=0.0024, Pcorr.LT.0.05) where the presence of the PAI-1 gene 4G allele appears to be one of the risk factors for periodontitis. (en)
- Periodontal diseases belong to the most common chronic disorders affecting mankind. Smoking and impaired plasminogen activation with hypercoagulation and fibrinolysis inhibition have been proposed as having a role in predisposition to these diseases We investigated relationships among adult periodontitis, smoking and a variation in the deletion/insertion (4G/5G) promoter polymorphism of the plasminogen-activator-inhibitor-1 (PAI-1) gene in 304 Caucasian subjects. An association was detected between the deletion (4G) allele (and 4G/4G genotype) and periodontitis (p=0.0022, Pcorr.LT.0.01, p=0.014, Pcorr.LT.0.05). Even a stronger association occurred in non-smokers (p=0.00021, Pcorr.LT.0.01, p=0.0024, Pcorr.LT.0.05) where the presence of the PAI-1 gene 4G allele appears to be one of the risk factors for periodontitis. (cs)
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| Title
| - Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers
- Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers (en)
- Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers (cs)
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| skos:prefLabel
| - Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers
- Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers (en)
- Plasminogen-Activator-Inhibitor-1 Promoter Polymorphism as a Risk Factor for Adult Periodontitis in Non-Smokers (cs)
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| skos:notation
| - RIV/00216224:14110/02:00005507!RIV09-MSM-14110___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00005507
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - gene; polymorphism; PAI-1; periodontitis (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Beneš, Petr
- Izakovičová-Hollá, Lydie
- Fassmann, Antonín
- Bučková, Dana
- Znojil, Vladimír
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| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
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| http://localhost/t...ganizacniJednotka
| |
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