About: Effect of retinoic acid on the actin cytoskeleton in HL-60 cells

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The morphological changes in actin cytoskeleton, taking place during apoptosis in cells of the human leukemic HL-60 cell line, were described. It is concluded that the actin cytoskeleton is a dynamic structure actively involved in the executive phase of the process of apoptosis. It is suggested that the rearrangement of the microfilament network and its subsequent degradation are necessary for the main morphological changes of apoptotic cells, i.e., plasma membrane blebbing and apoptotic bodies formation. The morphological changes in actin cytoskeleton, taking place during apoptosis in cells of the human leukemic HL-60 cell line, were described. It is concluded that the actin cytoskeleton is a dynamic structure actively involved in the executive phase of the process of apoptosis. It is suggested that the rearrangement of the microfilament network and its subsequent degradation are necessary for the main morphological changes of apoptotic cells, i.e., plasma membrane blebbing and apoptotic bodies formation. (en) The morphological changes in actin cytoskeleton, taking place during apoptosis in cells of the human leukemic HL-60 cell line, were described. It is concluded that the actin cytoskeleton is a dynamic structure actively involved in the executive phase of the process of apoptosis. It is suggested that the rearrangement of the microfilament network and its subsequent degradation are necessary for the main morphological changes of apoptotic cells, i.e., plasma membrane blebbing and apoptotic bodies formation. (cs)
Title	Effect of retinoic acid on the actin cytoskeleton in HL-60 cells Effect of retinoic acid on the actin cytoskeleton in HL-60 cells (en) Effect of retinoic acid on the actin cytoskeleton in HL-60 cells (cs)
skos:prefLabel	Effect of retinoic acid on the actin cytoskeleton in HL-60 cells Effect of retinoic acid on the actin cytoskeleton in HL-60 cells (en) Effect of retinoic acid on the actin cytoskeleton in HL-60 cells (cs)
skos:notation	RIV/00216224:14110/01:00005470!RIV08-GA0-14110___
http://linked.open.../vavai/riv/strany	456
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA304/00/0403)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Veselská, Renata Zitterbart, Karel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	678755
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/01:00005470
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Apoptosis; cytoskeleton; F-actin; all-trans retinoic acid; differentiation; HL-60 cells (en)
http://linked.open.../riv/klicoveSlovo	HL-60 cells F-actin Apoptosis cytoskeleton differentiation all-trans retinoic acid
http://linked.open...odStatuVydavatele	SK - Slovenská republika
http://linked.open...ontrolniKodProRIV	[9CD26215280D]
http://linked.open...i/riv/nazevZdroje	Neoplasma
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	48
http://linked.open...iv/tvurceVysledku	Veselská, Renata Zitterbart, Karel
issn	0028-2685
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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