About: Innovative surface modification of Ti-6Al-4V alloy with a positive effect on osteoblast proliferation and fatigue performance     Goto   Sponge   NotDistinct   Permalink

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Description
  • A novel approach of surface treatment of orthopaedic implants combining electric discharge machining (EDM), chemical milling (etching) and shot peening is presented in this study. Each of the three techniques have been used or proposed to be used as a favourable surface treatment of biomedical titanium alloys. But to our knowledge, the three techniques have not yet been used in combination. Surface morphology and chemistry were studied by scanning electron microscopy and X-ray photoelectron spectroscopy, respectively. Fatigue life of the material was determined and finally several in-vitro biocompatibility tests have been performed. EDM and subsequent chemical milling leads to a significant improvement of osteoblast proliferation and viability thanks to favourable surface morphology and increased oxygen content on the surface. Subsequent shot-peening significantly improves the fatigue endurance of the material. Material after proposed combined surface treatment possesses favourable mechanical properties and enhanced osteoblast proliferation. EDM treatment and EDM with shot peening also supported early osteogenic cell differentiation, manifested by a higher expression of collagen type I. The combined surface treatment is therefore promising for a range of applications in orthopaedics.
  • A novel approach of surface treatment of orthopaedic implants combining electric discharge machining (EDM), chemical milling (etching) and shot peening is presented in this study. Each of the three techniques have been used or proposed to be used as a favourable surface treatment of biomedical titanium alloys. But to our knowledge, the three techniques have not yet been used in combination. Surface morphology and chemistry were studied by scanning electron microscopy and X-ray photoelectron spectroscopy, respectively. Fatigue life of the material was determined and finally several in-vitro biocompatibility tests have been performed. EDM and subsequent chemical milling leads to a significant improvement of osteoblast proliferation and viability thanks to favourable surface morphology and increased oxygen content on the surface. Subsequent shot-peening significantly improves the fatigue endurance of the material. Material after proposed combined surface treatment possesses favourable mechanical properties and enhanced osteoblast proliferation. EDM treatment and EDM with shot peening also supported early osteogenic cell differentiation, manifested by a higher expression of collagen type I. The combined surface treatment is therefore promising for a range of applications in orthopaedics. (en)
Title
  • Innovative surface modification of Ti-6Al-4V alloy with a positive effect on osteoblast proliferation and fatigue performance
  • Innovative surface modification of Ti-6Al-4V alloy with a positive effect on osteoblast proliferation and fatigue performance (en)
skos:prefLabel
  • Innovative surface modification of Ti-6Al-4V alloy with a positive effect on osteoblast proliferation and fatigue performance
  • Innovative surface modification of Ti-6Al-4V alloy with a positive effect on osteoblast proliferation and fatigue performance (en)
skos:notation
  • RIV/00216208:11320/14:10287964!RIV15-MSM-11320___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GAP107/12/1025), P(TA01011141), S
http://linked.open...iv/cisloPeriodika
  • -
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 21949
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11320/14:10287964
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Osteogenic differentiation; Osteoblast viability; Mechanical properties; Surface roughness; Acid etching; Shot peening (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [10A2C2C9D8BA]
http://linked.open...i/riv/nazevZdroje
  • Materials Science and Engineering C
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 39
http://linked.open...iv/tvurceVysledku
  • Janeček, Miloš
  • Vandrovcová, Marta
  • Harcuba, Petr
  • Stráský, Josef
  • Bacakova, Lucie
  • Mhaede, Mansour
  • Havlikova, Jana
http://linked.open...ain/vavai/riv/wos
  • 000343949200049
issn
  • 0928-4931
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.msec.2014.03.024
http://localhost/t...ganizacniJednotka
  • 11320
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