About: Similarity Search and Posttranslational Modifications in Tandem Mass Spectra

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Tandem mass spectrometry is a fast and modern method for determining protein and peptide sequences from an %22in vitro%22 sample. A mass spectrometer outputs mass spectra, which are utilized for sequences identification. The successful methods for mass spectra interpretation are based on search in databases of already known or predicted protein sequences. Since the amount of protein sequences in the databases grows exponentially, couple of indexing approaches have been proposed to speed up the identification of the sequences corresponding to the mass spectra. However, many of these approaches do not (or poorly) support interpretation of the spectra contaminated with posttranslational modifications (PTMs), which in real-world conditions occur very often. We propose a promising method for dealing with PTMs in mass spectra, including efficient similarity search employing metric indexing. In this paper, we generalize a previously proposed method based on the parametrized Hausdorff distance. Tandem mass spectrometry is a fast and modern method for determining protein and peptide sequences from an %22in vitro%22 sample. A mass spectrometer outputs mass spectra, which are utilized for sequences identification. The successful methods for mass spectra interpretation are based on search in databases of already known or predicted protein sequences. Since the amount of protein sequences in the databases grows exponentially, couple of indexing approaches have been proposed to speed up the identification of the sequences corresponding to the mass spectra. However, many of these approaches do not (or poorly) support interpretation of the spectra contaminated with posttranslational modifications (PTMs), which in real-world conditions occur very often. We propose a promising method for dealing with PTMs in mass spectra, including efficient similarity search employing metric indexing. In this paper, we generalize a previously proposed method based on the parametrized Hausdorff distance. (en)
Title	Similarity Search and Posttranslational Modifications in Tandem Mass Spectra Similarity Search and Posttranslational Modifications in Tandem Mass Spectra (en)
skos:prefLabel	Similarity Search and Posttranslational Modifications in Tandem Mass Spectra Similarity Search and Posttranslational Modifications in Tandem Mass Spectra (en)
skos:notation	RIV/00216208:11320/10:10057171!RIV11-GA0-11320___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA201/09/0683), P(GD201/09/H057), S, Z(MSM0021620838)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Hoksza, David Novák, Jiří
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Matematicko-fyzikální fakulta
http://linked.open...dnocenehoVysledku	287325
http://linked.open...ai/riv/idVysledku	RIV/00216208:11320/10:10057171
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	peptide identification; similarity search; tandem mass spectrometry (en)
http://linked.open.../riv/klicoveSlovo	peptide identification similarity search tandem mass spectrometry
http://linked.open...ontrolniKodProRIV	[64371D60A1AD]
http://linked.open...v/mistoKonaniAkce	Hong Kong, China
http://linked.open...i/riv/mistoVydani	Hong Kong
http://linked.open...i/riv/nazevZdroje	Bioinformatics and Biomedicine Workshops
http://linked.open...in/vavai/riv/obor	IN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Similarity searching in very large multimedia databases Res Informatica
http://linked.open...UplatneniVysledku	2010
http://linked.open...iv/tvurceVysledku	Novák, Jiří Hoksza, David
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2010-12-18 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Moderní metody, struktury a systémy informatiky
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	IEEE
https://schema.org/isbn	978-1-4244-8302-0
http://localhost/t...ganizacniJednotka	11320

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