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Description
  • Aggregation effect in microarray data analysis distorts the correlations between gene expression levels and, in some sense, plays a role of technical noise. This aspect is especially important in network and association inference analyses. However, it is possible to construct statistical estimators which take aggregation into account to generate -clean-covariance of expression levels. Based on this estimator, we provide a method to find gene pairs having essentially different correlation structure.
  • Aggregation effect in microarray data analysis distorts the correlations between gene expression levels and, in some sense, plays a role of technical noise. This aspect is especially important in network and association inference analyses. However, it is possible to construct statistical estimators which take aggregation into account to generate -clean-covariance of expression levels. Based on this estimator, we provide a method to find gene pairs having essentially different correlation structure. (en)
Title
  • Toward Integration of Biological Noise: Aggregation Effect in Microarray Data Analysis
  • Toward Integration of Biological Noise: Aggregation Effect in Microarray Data Analysis (en)
skos:prefLabel
  • Toward Integration of Biological Noise: Aggregation Effect in Microarray Data Analysis
  • Toward Integration of Biological Noise: Aggregation Effect in Microarray Data Analysis (en)
skos:notation
  • RIV/00216208:11320/09:00206811!RIV10-MSM-11320___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620839)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 346541
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11320/09:00206811
http://linked.open...riv/jazykVysledku
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  • Toward; Integration; Biological; Noise; Aggregation; Effect; Microarray; Analysis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [B466FC806AFF]
http://linked.open...i/riv/mistoVydani
  • Chichester, UK
http://linked.open...vEdiceCisloSvazku
  • 1
http://linked.open...i/riv/nazevZdroje
  • Batch Effects and Noise in Microarray Experiments: Sources and Solutions
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Klebanov, Lev
  • Scherer, Andreas
http://linked.open...n/vavai/riv/zamer
number of pages
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  • John Wiley & Sons, Ltd
https://schema.org/isbn
  • 978-0-470-74138-2
http://localhost/t...ganizacniJednotka
  • 11320
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