About: Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis     Goto   Sponge   NotDistinct   Permalink

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Description
  • An undescribed Microsporum species was isolated from skin scales recovered from a 40-mm large, annular, scaling lesion on the wrist of a 46-year-old woman. The risk factors for dermatophyte infection in the patient were frequent work in the garden, hunting, and contact with dogs and horses. Direct microscopic examination of the scales revealed the presence of dermatophyte hyphae; when the samples were cultured, a morphologically similar fungus grew on all slants in pure culture. Both of these findings strongly suggested that the isolate was the true causal agent of infection. The possible geophilic nature of the species was based on phylogenetic analysis (internal transcribed spacer region of rDNA and beta-tubulin gene) that placed it in between species of the M. gypseum complex. However, its divergencies from all other Microsporum species exceeded 4% base pairs. Based on beta-tubulin phylogeny, the isolated species is a sister to M. gypseum. The species produces abundant chlamydospores and clumps of hyphae similar to those of ascomatal primordia but no conidia and ascospores. The species was unable to grow at 37 degrees C and does not grow on T6 basal medium, which is unlike other Microsporum species; hair perforation and urease tests were positive. The addition of histidine to the T6 medium resulted in rapid growth of the fungus. The phylogenetic evidence, morphology, growth parameters, and physiology justified the proposal that the isolate is a new species, M. aenigmaticum, sp. nov.
  • An undescribed Microsporum species was isolated from skin scales recovered from a 40-mm large, annular, scaling lesion on the wrist of a 46-year-old woman. The risk factors for dermatophyte infection in the patient were frequent work in the garden, hunting, and contact with dogs and horses. Direct microscopic examination of the scales revealed the presence of dermatophyte hyphae; when the samples were cultured, a morphologically similar fungus grew on all slants in pure culture. Both of these findings strongly suggested that the isolate was the true causal agent of infection. The possible geophilic nature of the species was based on phylogenetic analysis (internal transcribed spacer region of rDNA and beta-tubulin gene) that placed it in between species of the M. gypseum complex. However, its divergencies from all other Microsporum species exceeded 4% base pairs. Based on beta-tubulin phylogeny, the isolated species is a sister to M. gypseum. The species produces abundant chlamydospores and clumps of hyphae similar to those of ascomatal primordia but no conidia and ascospores. The species was unable to grow at 37 degrees C and does not grow on T6 basal medium, which is unlike other Microsporum species; hair perforation and urease tests were positive. The addition of histidine to the T6 medium resulted in rapid growth of the fungus. The phylogenetic evidence, morphology, growth parameters, and physiology justified the proposal that the isolate is a new species, M. aenigmaticum, sp. nov. (en)
Title
  • Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis
  • Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis (en)
skos:prefLabel
  • Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis
  • Microsporum aenigmaticum sp nov from M. gypseum complex, isolated as a cause of tinea corporis (en)
skos:notation
  • RIV/00216208:11310/14:10283947!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(EE2.3.20.0055), P(EE2.3.30.0003), S
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 29231
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/14:10283947
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • sterile fungi; skin infection; Onygenales; keratinophilic fungi; geophilic dermatophytes; Arthroderma (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [0C0F2544DDA8]
http://linked.open...i/riv/nazevZdroje
  • Medical Mycology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 52
http://linked.open...iv/tvurceVysledku
  • Hubka, Vít
  • Kolařík, Miroslav
  • Dobiáš, Radim
  • Dobiášová, Stanislava
http://linked.open...ain/vavai/riv/wos
  • 000339913600007
issn
  • 1369-3786
number of pages
http://bibframe.org/vocab/doi
  • 10.1093/mmy/myt033
http://localhost/t...ganizacniJednotka
  • 11310
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