About: Complementary roles of mouse lipocalins in chemical communication and immunity

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About: Complementary roles of mouse lipocalins in chemical communication and immunity Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1042/BST20140053
Description	A primary site of infection in mammals is the nostrils, representing the gate to the brain through olfactory and vomeronasal epithelia, eyes as a direct route to the brain via the optical nerve, and oral cavity representing the main route to the digestive tract. Similarly, pheromones, odorants and tastants enter animal bodies the same way. Therefore similar evolutionary forces might have shaped the evolution of systems for recognition of pathogens and chemical signals. This might have resulted in sharing various proteins among systems of recognition and filtering to decrease potential costs of evolving and utilizing unique biochemical pathways. This has been documented previously in, for example, multipurpose and widely distributed GPCRs (G-protein-coupled receptors). The aim of the present review is to explore potential functional overlaps or complementary functions of lipocalins in the system of perception of exogenous substances to reconstruct the evolutionary forces that might have shaped their synergistic functions. A primary site of infection in mammals is the nostrils, representing the gate to the brain through olfactory and vomeronasal epithelia, eyes as a direct route to the brain via the optical nerve, and oral cavity representing the main route to the digestive tract. Similarly, pheromones, odorants and tastants enter animal bodies the same way. Therefore similar evolutionary forces might have shaped the evolution of systems for recognition of pathogens and chemical signals. This might have resulted in sharing various proteins among systems of recognition and filtering to decrease potential costs of evolving and utilizing unique biochemical pathways. This has been documented previously in, for example, multipurpose and widely distributed GPCRs (G-protein-coupled receptors). The aim of the present review is to explore potential functional overlaps or complementary functions of lipocalins in the system of perception of exogenous substances to reconstruct the evolutionary forces that might have shaped their synergistic functions. (en)
Title	Complementary roles of mouse lipocalins in chemical communication and immunity Complementary roles of mouse lipocalins in chemical communication and immunity (en)
skos:prefLabel	Complementary roles of mouse lipocalins in chemical communication and immunity Complementary roles of mouse lipocalins in chemical communication and immunity (en)
skos:notation	RIV/00216208:11310/14:10282762!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP506/12/1046)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Stopka, Pavel Hájková, Petra Stopková, Romana Dudková, Barbora
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	8337
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/14:10282762
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pheromone; odorant-binding protein (OBP); odorant; major urinary protein (MUP); lipocalin; bacterium (en)
http://linked.open.../riv/klicoveSlovo	pheromone bacterium odorant lipocalin major urinary protein (MUP) odorant-binding protein (OBP)
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[B6BECD1AC8BD]
http://linked.open...i/riv/nazevZdroje	Biochemical Society Transactions
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Evolution of chemical communication in mammals and birds
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	42
http://linked.open...iv/tvurceVysledku	Hájková, Petra Stopka, Pavel Stopková, Romana Dudková, Barbora
http://linked.open...ain/vavai/riv/wos	000340329200028
issn	0300-5127
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1042/BST20140053
http://localhost/t...ganizacniJednotka	11310

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