About: Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU)     Goto   Sponge   NotDistinct   Permalink

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Description
  • An application of the flow differential pulse voltammetry with tubular detector based on silver solid amalgam for determination of antineoplastic drug lomustine in pharmaceutical preparations is presented. The highest sensitivity was obtained in [0.10moldm(-3) MES; 2.00moldm(-3) NaCl; pH6.0]:EtOH (9:1) with flow rate 0.50mLmin(-1), and the magnitude of the modulation amplitude -0.070V. The calibration dependence was linear in the range 1x10(-6)-1x10(-4)moldm(-3) (R-2=0.999). The limit of detection was 1.5x10(-7)moldm(-3). This method was successfully used for determination of lomustine in real samples of chemotherapy drug CeeNU Lomustine 40mg.
  • An application of the flow differential pulse voltammetry with tubular detector based on silver solid amalgam for determination of antineoplastic drug lomustine in pharmaceutical preparations is presented. The highest sensitivity was obtained in [0.10moldm(-3) MES; 2.00moldm(-3) NaCl; pH6.0]:EtOH (9:1) with flow rate 0.50mLmin(-1), and the magnitude of the modulation amplitude -0.070V. The calibration dependence was linear in the range 1x10(-6)-1x10(-4)moldm(-3) (R-2=0.999). The limit of detection was 1.5x10(-7)moldm(-3). This method was successfully used for determination of lomustine in real samples of chemotherapy drug CeeNU Lomustine 40mg. (en)
Title
  • Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU)
  • Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU) (en)
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  • Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU)
  • Application of Non-Stop-Flow Differential Pulse Voltammetry at a Tubular Detector of Silver Solid Amalgam for Electrochemical Determination of Lomustine (CCNU) (en)
skos:notation
  • RIV/00216208:11310/14:10210465!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita
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  • I, P(GBP206/12/G151), S
http://linked.open...iv/cisloPeriodika
  • 2
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  • 3794
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  • RIV/00216208:11310/14:10210465
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  • Lomustine; Chemotherapy drug; Silver solid amalgam; Tubular detector; Flow systems; Voltammetry (en)
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  • DE - Spolková republika Německo
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  • [9CB2E48CAAAB]
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  • Electroanalysis
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  • 26
http://linked.open...iv/tvurceVysledku
  • Barek, Jiří
  • Josypčuk, Bohdan
  • Josypčuk, Oksana
http://linked.open...ain/vavai/riv/wos
  • 000331982500011
issn
  • 1040-0397
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/elan.201300456
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  • 11310
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