About: The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold     Goto   Sponge   NotDistinct   Permalink

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Description
  • The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The only way to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model.
  • The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The only way to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model. (en)
Title
  • The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold
  • The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold (en)
skos:prefLabel
  • The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold
  • The Growth and Delivery of Mezenchymal and Limbal Stem Cells Using Copolymer Polyamide 6/12 Nanofiber Scaffold (en)
skos:notation
  • RIV/00216208:11310/13:10190914!RIV14-MSM-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, S, Z(MSM0021620858)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 76919
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/13:10190914
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ocular surface reconstruction; Polyamide 6/12 nanofiber scaffolds; Limbal stem cells; Mesenchymal stem cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [2DF3BA85A27F]
http://linked.open...i/riv/mistoVydani
  • New York
http://linked.open...vEdiceCisloSvazku
  • Part IV
http://linked.open...i/riv/nazevZdroje
  • Corneal Regenerative Medicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Holáň, Vladimír
  • Trošan, Peter
  • Javorková, Eliška
http://linked.open...n/vavai/riv/zamer
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/978-1-62703-432-6_13
http://purl.org/ne...btex#hasPublisher
  • Humana Press
https://schema.org/isbn
  • 978-1-62703-431-9
http://localhost/t...ganizacniJednotka
  • 11310
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