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Description
  • New voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite film in the role of a transducer was used for the investigation of the interaction between model carcinogenic substance (2-aminofluorene; one of the most extensively studied examples of the aromatic amine class of carcinogens) and calf thymus double-stranded DNA (dsDNA). The layer of dsDNA immobilized at the electrode surface was utilized as a biocomponent responsive interface. The biosensor was characterized regarding the detection of DNA damage (induced by direct interaction with 2-aminofluorene) using square wave voltammetric responses of the guanine and adenine moieties and cyclic voltammetric responses of the anionic redox indicator [Fe(CN)6]4-/3- present in the solution.
  • New voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite film in the role of a transducer was used for the investigation of the interaction between model carcinogenic substance (2-aminofluorene; one of the most extensively studied examples of the aromatic amine class of carcinogens) and calf thymus double-stranded DNA (dsDNA). The layer of dsDNA immobilized at the electrode surface was utilized as a biocomponent responsive interface. The biosensor was characterized regarding the detection of DNA damage (induced by direct interaction with 2-aminofluorene) using square wave voltammetric responses of the guanine and adenine moieties and cyclic voltammetric responses of the anionic redox indicator [Fe(CN)6]4-/3- present in the solution. (en)
Title
  • Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer
  • Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer (en)
skos:prefLabel
  • Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer
  • Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer (en)
skos:notation
  • RIV/00216208:11310/12:10126733!RIV13-GA0-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GBP206/12/G151), Z(MSM0021620857)
http://linked.open...iv/cisloPeriodika
  • April
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 178551
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/12:10126733
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • 2-aminofluorene; carbon film electrode; voltammetry; DNA damage detection; electrochemical DNA biosensor (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [AC3207BAAD1B]
http://linked.open...i/riv/nazevZdroje
  • Procedia Chemistry [online]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Barek, Jiří
  • Vyskočil, Vlastimil
http://linked.open...ain/vavai/riv/wos
  • 000313216900008
http://linked.open...n/vavai/riv/zamer
issn
  • 1876-6196
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.proche.2012.10.130
http://localhost/t...ganizacniJednotka
  • 11310
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