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Description
| - We present the design of activity-based probes for cathepsins D that are effective in a complex proteome. The probes consist of a binding module with a statin-containing peptidic core, a warhead module bearing a photoreactive group, and a reporter tag. The fluorescent and biotin tags make the probes a powerful tool for a wide range of %22in-gel%22 and %22on-blot%22 proteomic applications.
- We present the design of activity-based probes for cathepsins D that are effective in a complex proteome. The probes consist of a binding module with a statin-containing peptidic core, a warhead module bearing a photoreactive group, and a reporter tag. The fluorescent and biotin tags make the probes a powerful tool for a wide range of %22in-gel%22 and %22on-blot%22 proteomic applications. (en)
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Title
| - Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome
- Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome (en)
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skos:prefLabel
| - Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome
- Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome (en)
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skos:notation
| - RIV/00216208:11310/10:10108913!RIV12-MSM-11310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(IAA400550705), S, Z(AV0Z40550506), Z(AV0Z50520514)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11310/10:10108913
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - activity-based probes; cancer; cathepsin D; digestion; inhibitors; Identification (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Chembiochem : a European journal of chemical biology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Horn, Martin
- Mareš, Michael
- Máša, Martin
- Reiniš, Milan
- Srp, Jaroslav
- Šanda, Miloslav
- Hradílek, Martin
- Nussbaumerová, Martina
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
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http://localhost/t...ganizacniJednotka
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