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rdf:type
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Description
| - The metabolic transformation of mitochondria in distinct lineages of eukaryotes created proteomes ranging from thousands of proteins to what appear to be a much simpler scenario. In the case of Entamoeba histolytica, tiny mitochondria known as mitosomes have undergone extreme reduction. Only recently a single complete metabolic pathway of sulfate activation has been identified in these organelles. The E. histolytica mitosomes do not produce ATP needed for the sulfate activation pathway and for three molecular chaperones, Cpn60, Cpn10 and mtHsp70. We used a hidden Markov model (HMM) based search of the E. histolytica genome sequence to discover candidate (i) mitosomal phosphate carrier complementing the activity of the ADP/ATP carrier and (ii) membrane-located components of the protein import machinery that includes the outer membrane translocation channel Tom40 and membrane assembly protein Sam50.
- The metabolic transformation of mitochondria in distinct lineages of eukaryotes created proteomes ranging from thousands of proteins to what appear to be a much simpler scenario. In the case of Entamoeba histolytica, tiny mitochondria known as mitosomes have undergone extreme reduction. Only recently a single complete metabolic pathway of sulfate activation has been identified in these organelles. The E. histolytica mitosomes do not produce ATP needed for the sulfate activation pathway and for three molecular chaperones, Cpn60, Cpn10 and mtHsp70. We used a hidden Markov model (HMM) based search of the E. histolytica genome sequence to discover candidate (i) mitosomal phosphate carrier complementing the activity of the ADP/ATP carrier and (ii) membrane-located components of the protein import machinery that includes the outer membrane translocation channel Tom40 and membrane assembly protein Sam50. (en)
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Title
| - The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica
- The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica (en)
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skos:prefLabel
| - The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica
- The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica (en)
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skos:notation
| - RIV/00216208:11310/10:10080557!RIV11-MSM-11310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(LC07032), Z(MSM0021620858)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11310/10:10080557
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - yeast mitochondria; precursor proteins; remnant organelles; hydrogenosomes contain; saccharomyces-cerevisiae; encephalitozoon-cuniculi; microsporidian mitosomes; dictyostelium-discoideum; outer-membrane; Hidden markov-models (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Doležal, Pavel
- Lithgow, Trevor
- Tachezy, Jan
- Šedinová, Miroslava
- Bachmann, Anna
- Bruchhaus, Iris
- Dagley, Michael J.
- Foo, Jung Hock
- Kono, Maya
- Likic, Vladimir A.
- Wolynec, Peter
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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