About: Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption

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About: Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.chroma.2009.05.088
Description	A novel universal aerosol-based detector Nano Quantity Analyte Detector - NQAD (TM), connected with an ultra-performance liquid chromatography system is described. The detector was employed for detection of selected antibiotic compounds - macrolides (oleandomycin, erythromycin, troleandomycin, clarithromycin and roxithromycin) that are hard to detect using classical UV detectors due to the lack of chromophores. The determined lowest detection limits under isocratic conditions for these compounds ranged from 3.0 to 5.4 mu g/mL. The suitability of the detector connected with ultra high-performance liquid chromatography in the gradient mode was tested on a more complex mixture containing 12 antibiotics. The detector exhibited full compatibility under both the elution modes when UHPLC separations were achieved in relatively short run times. A novel universal aerosol-based detector Nano Quantity Analyte Detector - NQAD (TM), connected with an ultra-performance liquid chromatography system is described. The detector was employed for detection of selected antibiotic compounds - macrolides (oleandomycin, erythromycin, troleandomycin, clarithromycin and roxithromycin) that are hard to detect using classical UV detectors due to the lack of chromophores. The determined lowest detection limits under isocratic conditions for these compounds ranged from 3.0 to 5.4 mu g/mL. The suitability of the detector connected with ultra high-performance liquid chromatography in the gradient mode was tested on a more complex mixture containing 12 antibiotics. The detector exhibited full compatibility under both the elution modes when UHPLC separations were achieved in relatively short run times. (en)
Title	Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption (en)
skos:prefLabel	Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption Hyphenated ultra high-performance liquid chromatography-Nano Quantity Analyte Detector technique for determination of compounds with low UV absorption (en)
skos:notation	RIV/00216208:11310/09:10112578!RIV12-MSM-11310___
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(1M06011), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	30
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kameník, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	318225
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/09:10112578
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	UV detection; Macrolides; Nano Quantity Analyte Detector; Ultra high-performance liquid chromatography (en)
http://linked.open.../riv/klicoveSlovo	UV detection Ultra high-performance liquid chromatography Macrolides Nano Quantity Analyte Detector
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[4EF053D9F8FC]
http://linked.open...i/riv/nazevZdroje	Journal of Chromatography A
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	The Centre of Molecular Methods for Monitoring the Diffuse Pollution of the Environment.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	1216
http://linked.open...iv/tvurceVysledku	Kameník, Zdeněk Olšovská, Jana Cajtham, Tomáš
http://linked.open...ain/vavai/riv/wos	000268074800022
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	0021-9673
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.chroma.2009.05.088
http://localhost/t...ganizacniJednotka	11310

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