About: Sex in Leishmania

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Genetic exchange is crucial for adaptation to stressful environments. However, in Leishmania, exposure to specific stressful conditions in the sand fly gut is likely to induce genetic exchange. Access to the sand fly genome is now urgently required to facilitace the search for factors that stimulate Leishmania sex. The epidemiological consequences of genetic exchange in Leishmania are potentially alarming. Akopyants et al. demonstrate two distinct virulence traits among hybrid Leishmania clones but do not dokument the effect of genetic exchange on development of Leishmania in the vector. There is, however, proof that sex enhances Leishmania fitness and transmission in the sand fly. Leishmania infantum and L. major are divergent species, transmitted by different vectors to different mammalian reservoirs. Nevertheless, L. infantum/L. major hybrids complete the life cycle in Phlebotomus papatasi, the specific vector of L. major that does not support L. infantum. Genetic exchange is crucial for adaptation to stressful environments. However, in Leishmania, exposure to specific stressful conditions in the sand fly gut is likely to induce genetic exchange. Access to the sand fly genome is now urgently required to facilitace the search for factors that stimulate Leishmania sex. The epidemiological consequences of genetic exchange in Leishmania are potentially alarming. Akopyants et al. demonstrate two distinct virulence traits among hybrid Leishmania clones but do not dokument the effect of genetic exchange on development of Leishmania in the vector. There is, however, proof that sex enhances Leishmania fitness and transmission in the sand fly. Leishmania infantum and L. major are divergent species, transmitted by different vectors to different mammalian reservoirs. Nevertheless, L. infantum/L. major hybrids complete the life cycle in Phlebotomus papatasi, the specific vector of L. major that does not support L. infantum. (en)
Title	Sex in Leishmania Sex in Leishmania (en)
skos:prefLabel	Sex in Leishmania Sex in Leishmania (en)
skos:notation	RIV/00216208:11310/09:10000154!RIV10-MSM-11310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC06009), Z(MSM0021620828)
http://linked.open...iv/cisloPeriodika	5935
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Volf, Petr Sádlová, Jovana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	340978
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/09:10000154
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	sex; Leishmania infantum; hybrids (en)
http://linked.open.../riv/klicoveSlovo	sex Leishmania infantum hybrids
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[D6DA6C0136E6]
http://linked.open...i/riv/nazevZdroje	Science
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre for molecular ecology of vectors and pathogens
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	324
http://linked.open...iv/tvurceVysledku	Volf, Petr Sádlová, Jovana
http://linked.open...ain/vavai/riv/wos	000267338200014
http://linked.open...n/vavai/riv/zamer	Ekologické procesy v evoluci modelových skupin organismů
issn	0036-8075
number of pages	1 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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