About: Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor

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About: Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Regioisomer of chitobiose 13 with beta(1-->3) glycosidic bond and branched analog of chitotriose 25 having beta(1-->4) and beta(1-->3) glycosidic bonds, were prepared and tested as potential mimetics of natural oligosaccharide ligands for activating lectin receptors NKR-P1A and CD69 of natural killer (NK) cells. The structural requirements of NKR-P1 lectin receptor on effective mimetics of its natural ligands has been discussed. A significant binding activity of the branched trisaccharide 25 to the receptor CD69 was observed. Regioisomer of chitobiose 13 with beta(1-->3) glycosidic bond and branched analog of chitotriose 25 having beta(1-->4) and beta(1-->3) glycosidic bonds, were prepared and tested as potential mimetics of natural oligosaccharide ligands for activating lectin receptors NKR-P1A and CD69 of natural killer (NK) cells. The structural requirements of NKR-P1 lectin receptor on effective mimetics of its natural ligands has been discussed. A significant binding activity of the branched trisaccharide 25 to the receptor CD69 was observed. (en)
Title	Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor (en)
skos:prefLabel	Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Killer Cells NKR-P1 and CD69 Lectin Receptor (en)
skos:notation	RIV/00216208:11310/04:00006389!RIV10-GA0-11310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GA203/00/0071), S
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bezouška, Karel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	589351
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/04:00006389
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	synthesis of oligosaccharides; N-acetylglucosamine; mimetic; receptors of NK cells (en)
http://linked.open.../riv/klicoveSlovo	mimetic N-acetylglucosamine receptors of NK cells synthesis of oligosaccharides
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[93FCDF24F0F5]
http://linked.open...i/riv/nazevZdroje	Collection of Czechoslovak Chemical Communications
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthesis of cyclic oligosaccharides containing 2-amino-2-deoxy-hexopyranoses and study of their complexation activity
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	69
http://linked.open...iv/tvurceVysledku	Bezouška, Karel Šaman, David Ledvina, Miroslav Rohlenová, Anna
http://linked.open...ain/vavai/riv/wos	000224406800003
issn	0010-0765
number of pages	24 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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