About: Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase

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About: Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We found out that cardiomegally induced by pressure overload in newborn rats is associated with decreased content of the long form of G(s)alpha protein and impaired function of the catalytic subunit of adenylyl cyclase. We found out that cardiomegally induced by pressure overload in newborn rats is associated with decreased content of the long form of G(s)alpha protein and impaired function of the catalytic subunit of adenylyl cyclase. (en) Zjistili jsme, že kardiomegalie navozená tlakovou zátěží u novorozených potkanů je asociována se sníženým obsahem dlouhé formy G(s)alfa proteinu a s počkozenou funkcí katalytické podjednotky adenylylcyklasy. (cs)
Title	Kardiomegalie indukovaná tlakovou zátěží v novorozených potkanech je doprovázena změněnou expresí dlouhé isoformy Gs alfa proteinu a narušenou signalizací adenylylcyklasy (cs) Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase (en)
skos:prefLabel	Kardiomegalie indukovaná tlakovou zátěží v novorozených potkanech je doprovázena změněnou expresí dlouhé isoformy Gs alfa proteinu a narušenou signalizací adenylylcyklasy (cs) Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of Gs alpha protein and deranged signaling of adenylyl cyclase (en)
skos:notation	RIV/00216208:11310/03:12478!RIV08-MSM-11310___
http://linked.open.../vavai/riv/strany	157-166
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/00/1660), P(GA305/01/0279), P(LN00A069), Z(AV0Z5011922), Z(MSM 113100003)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Svoboda, Petr Novotný, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	600372
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/03:12478
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	rat myocardium; pressure overload; cardiomegaly; G-proteins; adenylyl cyclase; beta-adrenergic responsiveness; heterotrimeric g-proteins; cardiac-hypertrophy; heart-failure (en)
http://linked.open.../riv/klicoveSlovo	G-proteins adenylyl cyclase rat myocardium pressure overload heart-failure cardiomegaly cardiac-hypertrophy beta-adrenergic responsiveness heterotrimeric g-proteins
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[1A0B2BDEF57E]
http://linked.open...i/riv/nazevZdroje	Molecular and Cellular Biochemistry
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Physiological significance of the long and short variants of Gs-a protein Mechanisms of increased ischaemic tolerance in chronically hypoxic heart Center for experimental research of cardiovascular diseases
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	245
http://linked.open...iv/tvurceVysledku	Novotný, Jiří Svoboda, Petr
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100003
issn	0300-8177
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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