About: Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Alkaloidal extracts of seven selected plants of the family Papaveraceae were studied with respect to their activity against six strains of pathogenic bacteria and their alkaloidal fingerprint. Twenty-four alkaloids were determined by GC/MS, and twenty of them identified from their mass spectra, retention times and retention indexes. In the antibacterial assay, three Gram-positive (Enterorococcus faecalis, Staphylococcus aureus and S. hyicus), and three Gram-negative (Escherichia coli, Proteus mirabilis and Pseudomonas aeruginosa) strains were used. The most promising antimicrobial activity was shown by the alkaloidal extract of Macleaya cordata with MIC values of 16 mu g/mL for Staphylococcus aureus, 32 mu g/mL for Enterococcus faecalis and 64 mu g/mL for Staphylococcus hyicus and Escherichia coli. All the tested pure isoquinoline alkaloids were considered inactive within the tested concentrations. Alkaloidal extracts of seven selected plants of the family Papaveraceae were studied with respect to their activity against six strains of pathogenic bacteria and their alkaloidal fingerprint. Twenty-four alkaloids were determined by GC/MS, and twenty of them identified from their mass spectra, retention times and retention indexes. In the antibacterial assay, three Gram-positive (Enterorococcus faecalis, Staphylococcus aureus and S. hyicus), and three Gram-negative (Escherichia coli, Proteus mirabilis and Pseudomonas aeruginosa) strains were used. The most promising antimicrobial activity was shown by the alkaloidal extract of Macleaya cordata with MIC values of 16 mu g/mL for Staphylococcus aureus, 32 mu g/mL for Enterococcus faecalis and 64 mu g/mL for Staphylococcus hyicus and Escherichia coli. All the tested pure isoquinoline alkaloids were considered inactive within the tested concentrations. (en)
Title	Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants (en)
skos:prefLabel	Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants (en)
skos:notation	RIV/00216208:11160/14:10289765!RIV15-MSM-11160___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(EE2.3.20.0235), P(QI111A166), S
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Ločárek, Miroslav Šafratová, Marcela Cahlíková, Lucie Opletal, Lubomír Hošťálková, Anna Chlebek, Jakub Hulcová, Daniela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	3435
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/14:10289765
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Dihydrosanguinarine; Isoquinoline alkaloids; Macleaya microcarpa; Papaveraceae; GC/MS; Antimicrobial activity (en)
http://linked.open.../riv/klicoveSlovo	Antimicrobial activity Macleaya microcarpa Dihydrosanguinarine GC/MS Papaveraceae Isoquinoline alkaloids
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E3DB5B09DA51]
http://linked.open...i/riv/nazevZdroje	Natural product communications
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	11 (xsd:int)
http://linked.open...vavai/riv/projekt	Biotechnological processes in reproduction and pig breeding as a tool of the economic growth and competitive advantage. Establishment of Research Team Focused on Experimental and Applied Biopharmacy
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	9
http://linked.open...iv/tvurceVysledku	Rozkot, Miroslav Cahlíková, Lucie Chlebek, Jakub Hošťálková, Anna Opletal, Lubomír Klouček, Pavel Fraňková, Adéla Šmíd, Jakub Ločárek, Miroslav Šafratová, Marcela Hulcová, Daniela
http://linked.open...ain/vavai/riv/wos	000346892700011
issn	1934-578X
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	11160

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