About: Influence of ceramide on the internal structure and hydration of the phospholipid bilayer studied by neutron and X-ray scattering     Goto   Sponge   NotDistinct   Permalink

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  • Small angle neutron scattering (SANS), neutron diffraction and X-ray powder diffraction were used to investigate influence of N-stearoyl phytosphingosine (CER[NP]) and alpha-hydroxy-N-stearoyl phytosphingosine (CER[AP]) on the internal structure and hydration of DMPC membrane in fully and partly hydrated states at T = 30 A degrees C. Application of Fourier analysis for diffraction data and model calculations for the SANS data evidence that addition of both CER[NP] and CER[AP] in small concentrations promotes significant changes in the organization of DMPC bilayers, such as the increase of the hydrophobic core region. SANS data evidence a decrease in the average radius and polydispersity of the vesicles that can be ascribed to hydrogen bonds interactions that favor tight lipid packing with a compact, more rigid character.
  • Small angle neutron scattering (SANS), neutron diffraction and X-ray powder diffraction were used to investigate influence of N-stearoyl phytosphingosine (CER[NP]) and alpha-hydroxy-N-stearoyl phytosphingosine (CER[AP]) on the internal structure and hydration of DMPC membrane in fully and partly hydrated states at T = 30 A degrees C. Application of Fourier analysis for diffraction data and model calculations for the SANS data evidence that addition of both CER[NP] and CER[AP] in small concentrations promotes significant changes in the organization of DMPC bilayers, such as the increase of the hydrophobic core region. SANS data evidence a decrease in the average radius and polydispersity of the vesicles that can be ascribed to hydrogen bonds interactions that favor tight lipid packing with a compact, more rigid character. (en)
Title
  • Influence of ceramide on the internal structure and hydration of the phospholipid bilayer studied by neutron and X-ray scattering
  • Influence of ceramide on the internal structure and hydration of the phospholipid bilayer studied by neutron and X-ray scattering (en)
skos:prefLabel
  • Influence of ceramide on the internal structure and hydration of the phospholipid bilayer studied by neutron and X-ray scattering
  • Influence of ceramide on the internal structure and hydration of the phospholipid bilayer studied by neutron and X-ray scattering (en)
skos:notation
  • RIV/00216208:11160/14:10282025!RIV15-MSM-11160___
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  • 21341
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  • RIV/00216208:11160/14:10282025
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  • models; apoptosis; liposomes; stress; membrane; diffraction; cell regulation; unilamellar vesicles; lipid-bilayers (en)
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  • US - Spojené státy americké
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  • [01CC51BE40DE]
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  • Applied Physics A: Materials Science and Processing
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  • 116
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  • Zbytovská, Jarmila
  • Kiselev, M. A.
  • Lombardo, D.
  • Almasy, L.
  • Funari, S. S.
  • Hauss, T.
  • Ryabova, N. Y.
  • Zemlyanaya, E. V.
http://linked.open...ain/vavai/riv/wos
  • 000338214300040
issn
  • 0947-8396
number of pages
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  • 10.1007/s00339-013-8123-3
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  • 11160
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