About: Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://link.springer.com/chapter/10.1007/978-3-319-05458-2_62
Description	Novel imaging diagnostic method - wireless capsule enteroscopy was used in experimental gastroenterology studies in pigs. We monitored the disintegration of two types of drug forms in gastrointestinal tract for next optimalisation of pharmaceutical technology process. In parallel, the plasma time profiles of the active component were detected. In second study, scanning of intestinal mucous lesions was done as diagnostic tool. The disintegration of tablets was perceptible in the duodenal-jejunal segment (until the 90th min) and culminated in the proximal jejunum (at the 3rd hour). The peak of maximal concentration was reached between the 3rd and 6th hour. The most common lesions induced by non-steroidal anti-inflammatory drugs were red spots and erosions. Sensitivity and specificity of capsule endoscopy were more than 80% and 95%, respectively. Wireless capsule endoscopy is a highly accurate non-invasive method for evaluation of experimental NSAID-induced enteropathy and evaluation of tablet disintegration proces in the intestine. Novel imaging diagnostic method - wireless capsule enteroscopy was used in experimental gastroenterology studies in pigs. We monitored the disintegration of two types of drug forms in gastrointestinal tract for next optimalisation of pharmaceutical technology process. In parallel, the plasma time profiles of the active component were detected. In second study, scanning of intestinal mucous lesions was done as diagnostic tool. The disintegration of tablets was perceptible in the duodenal-jejunal segment (until the 90th min) and culminated in the proximal jejunum (at the 3rd hour). The peak of maximal concentration was reached between the 3rd and 6th hour. The most common lesions induced by non-steroidal anti-inflammatory drugs were red spots and erosions. Sensitivity and specificity of capsule endoscopy were more than 80% and 95%, respectively. Wireless capsule endoscopy is a highly accurate non-invasive method for evaluation of experimental NSAID-induced enteropathy and evaluation of tablet disintegration proces in the intestine. (en)
Title	Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches (en)
skos:prefLabel	Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches Imaging and Evaluating Method as Part of Endoscopical Diagnostic Approaches (en)
skos:notation	RIV/00216208:11160/14:10272259!RIV15-MSM-11160___
http://linked.open...avai/riv/aktivita	I S
http://linked.open...avai/riv/aktivity	I, S
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Nobilis, Milan
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	20486
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/14:10272259
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	drug forms; imaging method; enteropathy; Wireless capsule endoscopy (en)
http://linked.open.../riv/klicoveSlovo	imaging method enteropathy Wireless capsule endoscopy drug forms
http://linked.open...ontrolniKodProRIV	[0B22EFCEE329]
http://linked.open...v/mistoKonaniAkce	Bangkok
http://linked.open...i/riv/mistoVydani	Cham
http://linked.open...i/riv/nazevZdroje	Inteligent Information and Database Systems: 6th Asian Conference, ACIIDS 2014, Bangkok, Thailand, April 7-9, 2014, Proceedings, Part II
http://linked.open...in/vavai/riv/obor	IN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Bureš, Jan Kuča, Kamil Kuneš, Martin Květina, Jaroslav Kopáčová, Marcela Krejcar, Ondřej Tachecí, Ilja Nobilis, Milan
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2014-04-07 (xsd:date)
issn	0302-9743
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/978-3-319-05458-2_62
http://purl.org/ne...btex#hasPublisher	Spriger
https://schema.org/isbn	978-3-319-05458-2
http://localhost/t...ganizacniJednotka	11160

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