About: A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose

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About: A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.prolekare.cz/linkout/41242
Description	The paper studies the compressibility and disintegration time of tablets from the co-processed dry binder Disintequik MCC in combination with two lubricants at two concentrations in dependence on compression force. It also compares identical parameters in the physical mixtures of the spray-dried lactose Flowlac 100 and the microcrystalline cellulose Microcel MC-102 in the ratios of 1:9, 2:8 and 3:7 again in combination with two lubricants of two concentrations at one compression force. The lubricants employed are magnesium stearate and poloxamer 407 in concentrations of 1% and 2%. Compressibility is evaluated by means of energy balance of compression and tensile strength of tablets. The paper studies the compressibility and disintegration time of tablets from the co-processed dry binder Disintequik MCC in combination with two lubricants at two concentrations in dependence on compression force. It also compares identical parameters in the physical mixtures of the spray-dried lactose Flowlac 100 and the microcrystalline cellulose Microcel MC-102 in the ratios of 1:9, 2:8 and 3:7 again in combination with two lubricants of two concentrations at one compression force. The lubricants employed are magnesium stearate and poloxamer 407 in concentrations of 1% and 2%. Compressibility is evaluated by means of energy balance of compression and tensile strength of tablets. (en)
Title	A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose (en)
skos:prefLabel	A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose (en)
skos:notation	RIV/00216208:11160/13:10144249!RIV14-MSM-11160___
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Šináglová, Pavla Mužíková, Jitka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	59098
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/13:10144249
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	disintegration time of tablets; tensile strength of tablets; energy profile of compression; poloxamer 407; magnesium stearate; Disintequik MCC (en)
http://linked.open.../riv/klicoveSlovo	Disintequik MCC magnesium stearate poloxamer 407 disintegration time of tablets tensile strength of tablets energy profile of compression
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[E2B343F99B03]
http://linked.open...i/riv/nazevZdroje	Česká a slovenská farmacie
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	62
http://linked.open...iv/tvurceVysledku	Mužíková, Jitka Šináglová, Pavla
issn	1210-7816
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11160

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