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Description
  • A searching for some possibilities how to increase DOX efficacy in cancer cells and minimizing associated toxicities to non-cancerous tissues is in the forefront of scientific research. This study showed that isoquinoline derivative oracin significantly increased antiproliferative effect of cytostic drug doxorubicin in cancer cells and simultaneously decreased its toxicity in non-tumorous cells.
  • A searching for some possibilities how to increase DOX efficacy in cancer cells and minimizing associated toxicities to non-cancerous tissues is in the forefront of scientific research. This study showed that isoquinoline derivative oracin significantly increased antiproliferative effect of cytostic drug doxorubicin in cancer cells and simultaneously decreased its toxicity in non-tumorous cells. (en)
Title
  • Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase
  • Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase (en)
skos:prefLabel
  • Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase
  • Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase (en)
skos:notation
  • RIV/00216208:11160/12:10124816!RIV13-MSM-11160___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GBP303/12/G163), P(GP524/09/P121), S
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 153215
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11160/12:10124816
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • GST activity staining; structure-activity relationship; inhibition kinetics; IC50; gallocatechin gallate; flavonoids; glutathione S-transferase (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [38CDB1F8BC36]
http://linked.open...i/riv/nazevZdroje
  • Xenobiotica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 42
http://linked.open...iv/tvurceVysledku
  • Boušová, Iva
  • Dršata, Jaroslav
  • Hájek, Jan
  • Skálová, Lenka
http://linked.open...ain/vavai/riv/wos
  • 000307301900006
issn
  • 0049-8254
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/00498254.2012.670737
http://localhost/t...ganizacniJednotka
  • 11160
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