About: Antioxidant Polymers by Chitosan Modification

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://onlinelibrary.wiley.com/doi/10.1002/9781118445440.ch5/summary
Description	Oxidative stress induced by free radicals is a major factor in cell damage and is responsible for various kinds of diseases. Naturally abundant, chitosan is a perspective cationic polysaccharide which demonstrates scavenging free radical and antioxidant activity. Its antioxidant activity and water solubility depends on the molecular weight and degree of deacetylation. Even if the exact mechanism of activity is unknown, it is assumed that an amino group and hydroxyl groups react with unstable free radicals to form more stable macromolecular radicals. Efforts to improve the antioxidant activity of chitosan led to the grafting of natural or synthetic antioxidant molecules on chitosan. Modification of chitosan molecule by carboxymethylation, quaternization, sulphation, sulphonation, and Schiff base preparation brings more active derivatives. The most frequently used antioxidants, like phenolic compounds, gallic acid, caffeic acid, substituted hydroxyanisole, hydroxytoluene, and green tea extracts were incorporated into the chitosan molecule to improve its antioxidant activity. Oxidative stress induced by free radicals is a major factor in cell damage and is responsible for various kinds of diseases. Naturally abundant, chitosan is a perspective cationic polysaccharide which demonstrates scavenging free radical and antioxidant activity. Its antioxidant activity and water solubility depends on the molecular weight and degree of deacetylation. Even if the exact mechanism of activity is unknown, it is assumed that an amino group and hydroxyl groups react with unstable free radicals to form more stable macromolecular radicals. Efforts to improve the antioxidant activity of chitosan led to the grafting of natural or synthetic antioxidant molecules on chitosan. Modification of chitosan molecule by carboxymethylation, quaternization, sulphation, sulphonation, and Schiff base preparation brings more active derivatives. The most frequently used antioxidants, like phenolic compounds, gallic acid, caffeic acid, substituted hydroxyanisole, hydroxytoluene, and green tea extracts were incorporated into the chitosan molecule to improve its antioxidant activity. (en)
Title	Antioxidant Polymers by Chitosan Modification Antioxidant Polymers by Chitosan Modification (en)
skos:prefLabel	Antioxidant Polymers by Chitosan Modification Antioxidant Polymers by Chitosan Modification (en)
skos:notation	RIV/00216208:11160/12:10124282!RIV13-MSM-11160___
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Vinšová, Jarmila
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	122986
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/12:10124282
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	carboxymethyl chitosan; antioxidant activity; reactive oxygen species; chitosan (en)
http://linked.open.../riv/klicoveSlovo	antioxidant activity carboxymethyl chitosan reactive oxygen species chitosan
http://linked.open...ontrolniKodProRIV	[3DA1A739D0EF]
http://linked.open...i/riv/mistoVydani	Hoboken (USA)
http://linked.open...i/riv/nazevZdroje	Antioxidant Polymers : Synthesis, Properties, and Applications
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	493 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Vavříková, Eva Vinšová, Jarmila
number of pages	14 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Wiley
https://schema.org/isbn	978-1-118-20854-0
http://localhost/t...ganizacniJednotka	11160

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