About: New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture

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About: New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.tswj.com/2012/746412/
Description	The production of secondary metabolites in Trifolium pratense L. suspension culture of the family of legume plants (Fabaceae) is low, and therefore there was an attempt to increase it by elicitation. New synthetic substance, 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide, was tested as elicitor-a substance that showed the best elicitation effect after 48-hour application of 1 mu mol L-1 concentration. Maximum contents of genistin (11.60 mg g(-1) DW), daidzein (8.31 mg g(-1) DW), and genistein (1.50 mg g(-1) DW) were recorded, and the production of these isoflavonoids thus significantly increased, when compared with the control, by 152%, 151%, and 400%. The maximum content of flavonoids (5.78 mg g(-1) DW) and the increase in the production by 142%, when compared with the control, were induced by 6-hour application of 100 mu mol L-1 concentration. The tested substance showed to be an effective elicitor of phenylpropane metabolism. The production of secondary metabolites in Trifolium pratense L. suspension culture of the family of legume plants (Fabaceae) is low, and therefore there was an attempt to increase it by elicitation. New synthetic substance, 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide, was tested as elicitor-a substance that showed the best elicitation effect after 48-hour application of 1 mu mol L-1 concentration. Maximum contents of genistin (11.60 mg g(-1) DW), daidzein (8.31 mg g(-1) DW), and genistein (1.50 mg g(-1) DW) were recorded, and the production of these isoflavonoids thus significantly increased, when compared with the control, by 152%, 151%, and 400%. The maximum content of flavonoids (5.78 mg g(-1) DW) and the increase in the production by 142%, when compared with the control, were induced by 6-hour application of 100 mu mol L-1 concentration. The tested substance showed to be an effective elicitor of phenylpropane metabolism. (en)
Title	New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture (en)
skos:prefLabel	New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture New Synthetic Pyridine Derivate as Potential Elicitor in Production of Isoflavonoids and Flavonoids in Trifolium pratense L. Suspension Culture (en)
skos:notation	RIV/00216208:11160/12:10118797!RIV13-MSM-11160___
http://linked.open...avai/riv/aktivita	I S Z
http://linked.open...avai/riv/aktivity	I, S, Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	2012
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Klimešová, Věra Dušek, Jaroslav Kašparová, Marie Siatka, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	154125
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/12:10118797
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	flavonoids; isoflavonoids; Trifolium pratense L. suspension culture; elicitation; 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide (en)
http://linked.open.../riv/klicoveSlovo	elicitation flavonoids isoflavonoids 2-(2-fluoro-6-nitrobenzylsulfanyl)pyridine-4-carbothioamide Trifolium pratense L. suspension culture
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[0E681C90FB49]
http://linked.open...i/riv/nazevZdroje	The Scientific World Journal
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	2012
http://linked.open...iv/tvurceVysledku	Dušek, Jaroslav Klimešová, Věra Siatka, Tomáš Kašparová, Marie
http://linked.open...ain/vavai/riv/wos	000303022700001
http://linked.open...n/vavai/riv/zamer	Research of new drug structures
issn	1537-744X
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1100/2012/746412
http://localhost/t...ganizacniJednotka	11160

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