About: Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case

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About: Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S0021967310016249
Description	Hydrophilic interaction liquid chromatography (HILIC) was used to analyze dexrazoxane and its three metabolites on different stationary phases. Initial experiments were done with HPLC-UV and subsequently LC-MS were used to confirm applicability of the selected conditions. In addition, LC-MS behavior of all analytes were studied and characterized. Hydrophilic interaction liquid chromatography (HILIC) was used to analyze dexrazoxane and its three metabolites on different stationary phases. Initial experiments were done with HPLC-UV and subsequently LC-MS were used to confirm applicability of the selected conditions. In addition, LC-MS behavior of all analytes were studied and characterized. (en)
Title	Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case (en)
skos:prefLabel	Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites - The cardioprotectant dexrazoxane as a model case (en)
skos:notation	RIV/00216208:11160/11:10100602!RIV12-GA0-11160___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GPP206/10/P439), Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hrušková, Kateřina Kovaříková, Petra Vávrová, Kateřina Klimeš, Jiří Stariat, Ján
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	203154
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/11:10100602
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	LC-MS; Polar drug; Bisdioxopiperazine; Dexrazoxane; Hydrophilic interaction liquid chromatography (en)
http://linked.open.../riv/klicoveSlovo	LC-MS Bisdioxopiperazine Dexrazoxane Hydrophilic interaction liquid chromatography Polar drug
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[1CB530440F0E]
http://linked.open...i/riv/nazevZdroje	Journal of Chromatography A
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Modern bioanalytical contribution to the interdisciplinary investigation of bisdioxopiperazine cardioprotective agents.
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	1218
http://linked.open...iv/tvurceVysledku	Hrušková, Kateřina Klimeš, Jiří Kovaříková, Petra Vávrová, Kateřina Stariat, Ján
http://linked.open...ain/vavai/riv/wos	000286680900008
http://linked.open...n/vavai/riv/zamer	Research of new drug structures
issn	0021-9673
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.chroma.2010.11.050
http://localhost/t...ganizacniJednotka	11160

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