About: In vitro analysis of iron chelating activity of flavonoids

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S0162013411000316
Description	26 flavonoids were analyzed for their iron chelating activity and stability of the formed complexes in four patho/physiologically relevant pH conditions (4.5, 5.5, 6.8, 7.5) and compared with clinically used iron chelator deferoxamine. The study demonstrated that the most effective iron binding site of flavonoids represented 6,7-dihydroxy structure present in baicalein which was not inferior in all tested pH to deferoxamine. 26 flavonoids were analyzed for their iron chelating activity and stability of the formed complexes in four patho/physiologically relevant pH conditions (4.5, 5.5, 6.8, 7.5) and compared with clinically used iron chelator deferoxamine. The study demonstrated that the most effective iron binding site of flavonoids represented 6,7-dihydroxy structure present in baicalein which was not inferior in all tested pH to deferoxamine. (en)
Title	In vitro analysis of iron chelating activity of flavonoids In vitro analysis of iron chelating activity of flavonoids (en)
skos:prefLabel	In vitro analysis of iron chelating activity of flavonoids In vitro analysis of iron chelating activity of flavonoids (en)
skos:notation	RIV/00216208:11160/11:10100446!RIV12-MSM-11160___
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Macáková, Kateřina Jahodář, Luděk Filipský, Tomáš Zatloukalová, Libuše Mladěnka, Přemysl Hrdina, Radomír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	204027
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/11:10100446
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Deferoxamine; Antioxidants; Ferrozine; Chelation; Iron; Flavonoids (en)
http://linked.open.../riv/klicoveSlovo	Chelation Deferoxamine Ferrozine Iron Antioxidants Flavonoids
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[EF17069C539F]
http://linked.open...i/riv/nazevZdroje	Journal of Inorganic Biochemistry
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	105
http://linked.open...iv/tvurceVysledku	Macáková, Kateřina Bovicelli, Paolo Filipský, Tomáš Hrdina, Radomír Jahodář, Luděk Mladěnka, Přemysl Proietti Silvestri, Ilaria Saso, Luciano Zatloukalová, Libuše
http://linked.open...ain/vavai/riv/wos	000290923100014
issn	0162-0134
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.jinorgbio.2011.02.003
http://localhost/t...ganizacniJednotka	11160

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