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Description
| - In the report, we show a suppressive effect of metformin on PXR and other ligand-activated nuclear receptors in transactivation of the main detoxification enzyme CYP3A4 in human hepatocytes.
- In the report, we show a suppressive effect of metformin on PXR and other ligand-activated nuclear receptors in transactivation of the main detoxification enzyme CYP3A4 in human hepatocytes. (en)
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Title
| - Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene
- Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene (en)
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skos:prefLabel
| - Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene
- Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene (en)
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skos:notation
| - RIV/00216208:11160/11:10100402!RIV12-GA0-11160___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA303/07/0128), P(GAP304/10/0149), S
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11160/11:10100402
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - AMPK; PXR; induction; cytochrome P450; metformin (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Dvořák, Zdeněk
- Pávek, Petr
- Vrzal, Radim
- Stejskalová, Lucie
- Krausová, Lucie
- Mani, Sridhar
- Wang, Hongwei
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.bcp.2011.08.023
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http://localhost/t...ganizacniJednotka
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