About: Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes

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About: Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The study examined stereoselective interaction of R- ans S-enantiomers of warfarin with PXR nuclear receptor, which controls the most important cytochrome P450 enzymes. The study examined stereoselective interaction of R- ans S-enantiomers of warfarin with PXR nuclear receptor, which controls the most important cytochrome P450 enzymes. (en)
Title	Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes (en)
skos:prefLabel	Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes (en)
skos:notation	RIV/00216208:11160/10:00300649!RIV11-GA0-11160___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA303/07/0128), P(GAP304/10/0149), P(LC06063), S, Z(AV0Z50520514)
http://linked.open...iv/cisloPeriodika	12
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Prokopová, Iva Pávek, Petr Bitman, Michal Rulcová, Alice Krausová, Lucie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	290086
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/10:00300649
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	CYP3A4; cytochrome P450; enantiomers; gene regulation; PXR; warfarin (en)
http://linked.open.../riv/klicoveSlovo	CYP3A4 warfarin cytochrome P450 gene regulation enantiomers PXR
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2A259E46082B]
http://linked.open...i/riv/nazevZdroje	Journal of Thrombosis and Haemostasis
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Study on tissue-specific aspects of transcriptional regulation of selected P-450 enzymes and drug transporters. Generation of hepatocyte-derived cellular models for preclinical testing of drugs Flurescence microscopy in biological and medical research
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Blahoš, Jaroslav Dvořák, Zdeněk Pávek, Petr Vrzal, Radim Bitman, Michal Prokopová, Iva Rulcová, Alice Krausová Švecová, Lucie
http://linked.open...ain/vavai/riv/wos	000285110700016
http://linked.open...n/vavai/riv/zamer	Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
issn	1538-7933
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	11160

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