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rdf:type
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Description
| - This work was aimed to clarify, whether efavirenz induces ABC-transporters in vivo in PBMCs and whether possible changes in PBMC transporter expression also translate into altered intracellular concentrations of efavirenz. New analytical methods for quantification of efavirenz in plasma, plasma ultrafiltrate and PBMCs were developed. The samples were analyzed by LC/MS/MS.
- This work was aimed to clarify, whether efavirenz induces ABC-transporters in vivo in PBMCs and whether possible changes in PBMC transporter expression also translate into altered intracellular concentrations of efavirenz. New analytical methods for quantification of efavirenz in plasma, plasma ultrafiltrate and PBMCs were developed. The samples were analyzed by LC/MS/MS. (en)
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Title
| - No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment
- No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment (en)
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skos:prefLabel
| - No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment
- No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment (en)
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skos:notation
| - RIV/00216208:11160/10:00300623!RIV11-MSM-11160___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11160/10:00300623
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - efavirenz; ABC-transporters; P-glycoprotein; drug transport; pharmacokinetics (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Antimicrobial Agents and Chemotherapy
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Pasáková, Ivana
- Burhenne, Jürgen
- Haefeli, Walter Emil
- Heinrich, Tilman
- Matthée, Anne-Kathrin
- Mikus, Gerd
- Röder, Claudia
- Weiss, Johanna
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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