About: Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells

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About: Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The paper describes the effects of Orlistat on CYP3A4 gene expression via pregnane X receptor in primary human hepatocytes and human intestinal LS174T cells. The paper describes the effects of Orlistat on CYP3A4 gene expression via pregnane X receptor in primary human hepatocytes and human intestinal LS174T cells. (en)
Title	Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells (en)
skos:prefLabel	Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells (en)
skos:notation	RIV/00216208:11160/10:00300595!RIV11-GA0-11160___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GA303/07/0128), P(GAP304/10/0149), P(GAP503/10/0579), S
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Pávek, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	264830
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/10:00300595
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cytochrome P450; drug interactions; enzyme induction; orlistat; drug metabolism (en)
http://linked.open.../riv/klicoveSlovo	drug interactions drug metabolism cytochrome P450 orlistat enzyme induction
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[E6B5099A8B71]
http://linked.open...i/riv/nazevZdroje	European Journal of Pharmaceutical Sciences
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Study on tissue-specific aspects of transcriptional regulation of selected P-450 enzymes and drug transporters. Generation of hepatocyte-derived cellular models for preclinical testing of drugs Study of potential interaction of constituents of non-alcoholic beverages with signaling pathways involved in drug metabolism and carcinogenesis
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	41
http://linked.open...iv/tvurceVysledku	Dvořák, Zdeněk Dořičáková, Aneta Novotná, Aneta Pávek, Petr Vrzal, Radim Maurel, Patrick
http://linked.open...ain/vavai/riv/wos	000281995200010
issn	0928-0987
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11160

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