About: Breast cancer and cancer stem cells: a mini-review

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.tumorionline.it/r.php?v=1636&a=17886&l=26486&f=allegati/01636_2014_04/fulltext/01-Filipova%20363-369.pdf
Description	Breast cancer is the most common type of malignant disease in women worldwide. In developing countries the past few years have sustained an increasing incidence of this type of cancer. Currently, breast cancer is the second leading cause of death due to cancer in women. In 2008 alone it was diagnosed in more than 1 million patients and each year the number of breast cancer-related deaths is estimated to be ~450,000. The mortality rate in breast cancer patients has been decreasing over the years thanks to the development of early diagnostic methods and more effective treatments. But despite the new advances in cancer diagnosis and treatment, the risk of recurrence and metastasis is ever present. It has been theorized that cancer stem cells are involved in the process of tumor growth and metastases. Due to their self-renewing and differentiation capabilities, they are now considered the underlying factor in tumor recurrence and the main reason for therapy resistance. Therefore, the characterization of cancer stem cells may contribute to the development of more effective treatment strategies that should make it possible to eliminate cancer stem cells in order to prevent tumor relapse and metastasis in diagnosed patients. Breast cancer is the most common type of malignant disease in women worldwide. In developing countries the past few years have sustained an increasing incidence of this type of cancer. Currently, breast cancer is the second leading cause of death due to cancer in women. In 2008 alone it was diagnosed in more than 1 million patients and each year the number of breast cancer-related deaths is estimated to be ~450,000. The mortality rate in breast cancer patients has been decreasing over the years thanks to the development of early diagnostic methods and more effective treatments. But despite the new advances in cancer diagnosis and treatment, the risk of recurrence and metastasis is ever present. It has been theorized that cancer stem cells are involved in the process of tumor growth and metastases. Due to their self-renewing and differentiation capabilities, they are now considered the underlying factor in tumor recurrence and the main reason for therapy resistance. Therefore, the characterization of cancer stem cells may contribute to the development of more effective treatment strategies that should make it possible to eliminate cancer stem cells in order to prevent tumor relapse and metastasis in diagnosed patients. (en)
Title	Breast cancer and cancer stem cells: a mini-review Breast cancer and cancer stem cells: a mini-review (en)
skos:prefLabel	Breast cancer and cancer stem cells: a mini-review Breast cancer and cancer stem cells: a mini-review (en)
skos:notation	RIV/00216208:11150/14:10281272!RIV15-MSM-11150___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(EE2.3.30.0022)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Filipová, Alžběta Seifrtová, Martina Řezáčová, Martina Filip, Stanislav Mokrý, Jaroslav Diaz Garcia, Daniel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	5789
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/14:10281272
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	niche; metastasis; stem cells; cancer; Breast cancer (en)
http://linked.open.../riv/klicoveSlovo	stem cells niche Breast cancer cancer metastasis
http://linked.open...odStatuVydavatele	IT - Italská republika
http://linked.open...ontrolniKodProRIV	[99BEE9E15A9A]
http://linked.open...i/riv/nazevZdroje	Tumori
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Support of establishment, development, and mobility of quality research teams at the Charles University
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	100
http://linked.open...iv/tvurceVysledku	Dvořák, Josef Filip, Stanislav Mokrý, Jaroslav Řezáčová, Martina Seifrtová, Martina Filipová, Alžběta Diaz Garcia, Daniel
http://linked.open...ain/vavai/riv/wos	000348335300001
issn	0300-8916
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1700/1636.17886
http://localhost/t...ganizacniJednotka	11150

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