About: Hepatic Arterial Infusion for Biliary Tract Carcinoma: Single-center Experience

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aim: The aim of the present study was to evaluate a single-center experience in hepatic arterial infusion (HAI) of patients with biliary tract carcinomas. Patients and Methods: A retrospective analysis of 60 patients treated between 1997 and 2011 was performed. Results: Most patients were treated with HAI of a combination of 5-fluorouracil, folinic acid and cisplatin. The response was not evaluable in most patients, predominantly because of prior surgical procedures. The median survival of all patients was 15.1 months (5-year survival=13%). The survival was significantly better in patients treated with radical surgery (median=50.1 months, 5-year survival=45%) or palliative surgery (median=22.5 months, 5-year survival=13%) compared to no surgery (median=7.6 months, 5-year survival=3%). Conclusion: The current data demonstrate the efficacy of HAI in patients with biliary tract carcinoma. HAI is a therapeutic method to be considered in patients with inoperable biliary tract carcinoma and no extrahepatic spread. Aim: The aim of the present study was to evaluate a single-center experience in hepatic arterial infusion (HAI) of patients with biliary tract carcinomas. Patients and Methods: A retrospective analysis of 60 patients treated between 1997 and 2011 was performed. Results: Most patients were treated with HAI of a combination of 5-fluorouracil, folinic acid and cisplatin. The response was not evaluable in most patients, predominantly because of prior surgical procedures. The median survival of all patients was 15.1 months (5-year survival=13%). The survival was significantly better in patients treated with radical surgery (median=50.1 months, 5-year survival=45%) or palliative surgery (median=22.5 months, 5-year survival=13%) compared to no surgery (median=7.6 months, 5-year survival=3%). Conclusion: The current data demonstrate the efficacy of HAI in patients with biliary tract carcinoma. HAI is a therapeutic method to be considered in patients with inoperable biliary tract carcinoma and no extrahepatic spread. (en)
Title	Hepatic Arterial Infusion for Biliary Tract Carcinoma: Single-center Experience Hepatic Arterial Infusion for Biliary Tract Carcinoma: Single-center Experience (en)
skos:prefLabel	Hepatic Arterial Infusion for Biliary Tract Carcinoma: Single-center Experience Hepatic Arterial Infusion for Biliary Tract Carcinoma: Single-center Experience (en)
skos:notation	RIV/00216208:11150/13:10195440!RIV14-MSM-11150___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(ED0030/01/01)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Ferko, Alexander Krajina, Antonín Rozkoš, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	77221
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/13:10195440
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hepatic arterial infusion; gallbladder carcinoma; Cholangiocarcinoma (en)
http://linked.open.../riv/klicoveSlovo	hepatic arterial infusion gallbladder carcinoma Cholangiocarcinoma
http://linked.open...odStatuVydavatele	GR - Řecká republika
http://linked.open...ontrolniKodProRIV	[1433DD218785]
http://linked.open...i/riv/nazevZdroje	Anticancer Research
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Biomedicine for regional development and human resources
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	33
http://linked.open...iv/tvurceVysledku	Dvořák, Josef Ferko, Alexander Krajina, Antonín Melichar, Bohuslav Rozkoš, Tomáš Vobořil, Zbyněk
http://linked.open...ain/vavai/riv/wos	000316770400063
issn	0250-7005
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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