About: Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors

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About: Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.cskb.cz/res/file/KBM-pdf/2013/2013-3/abstrakta/Ab-KBM_3_2013-Drastikova-129.pdf
Description	Our aim was to determine the somatostatin (SSTR1-5) and estrogen receptor 1 (ER1) expression profile in 69 specimens of NFA. The expression of the receptors was determined by quantitative real time PCR. Results were normalized to the beta-glucuronidase housekeeping gene. With exceptions of SSTR4 and SSTR5, all other subtypes of receptors were expressed in the examined tumor specimens. The median relative quantification values were: 63.8% for SSTR1, 55.4% for SSTR2, 19.6% for SSTR3, 2.6% for SSTR4, 9.2% for SSTR5, and 75.4% for ER1. Our aim was to determine the somatostatin (SSTR1-5) and estrogen receptor 1 (ER1) expression profile in 69 specimens of NFA. The expression of the receptors was determined by quantitative real time PCR. Results were normalized to the beta-glucuronidase housekeeping gene. With exceptions of SSTR4 and SSTR5, all other subtypes of receptors were expressed in the examined tumor specimens. The median relative quantification values were: 63.8% for SSTR1, 55.4% for SSTR2, 19.6% for SSTR3, 2.6% for SSTR4, 9.2% for SSTR5, and 75.4% for ER1. (en)
Title	Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors (en)
skos:prefLabel	Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors Molecular biology investigation of somatostatin and estrogen receptors in clinically non-functioning pituitary tumors (en)
skos:notation	RIV/00216208:11150/13:10173513!RIV14-MZ0-11150___
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(NT11344), S
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Beránek, Martin Drastíková, Monika Čáp, Jan Gabalec, Filip
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	89290
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/13:10173513
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PCR; receptor; Somatostatin (en)
http://linked.open.../riv/klicoveSlovo	PCR receptor Somatostatin
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[44599D045905]
http://linked.open...i/riv/nazevZdroje	Klinická biochemie a metabolismus
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Quantitative analysis of somatostatin receptors in pituitary adenomas.
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Beránek, Martin Drastíková, Monika Čáp, Jan Gabalec, Filip
issn	1210-7921
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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