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Description
| - Introduction: The brain is one of the first organs affected clinically in sepsis. Microcirculatory alterations are suggested to be a critical component in the pathophysiology of sepsis. The aim of this study was to investigate the effects of recombinant human activated protein C (rhAPC) on the pial microcirculation in experimental endotoxemia using intravital microscopy. Our hypothesis is rhAPC protects pial microcirculation in endotoxemia.
- Introduction: The brain is one of the first organs affected clinically in sepsis. Microcirculatory alterations are suggested to be a critical component in the pathophysiology of sepsis. The aim of this study was to investigate the effects of recombinant human activated protein C (rhAPC) on the pial microcirculation in experimental endotoxemia using intravital microscopy. Our hypothesis is rhAPC protects pial microcirculation in endotoxemia. (en)
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Title
| - Activated protein C improves pial microcirculation in experimental endotoxemia in rats
- Activated protein C improves pial microcirculation in experimental endotoxemia in rats (en)
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skos:prefLabel
| - Activated protein C improves pial microcirculation in experimental endotoxemia in rats
- Activated protein C improves pial microcirculation in experimental endotoxemia in rats (en)
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skos:notation
| - RIV/00216208:11150/12:10126972!RIV13-MSM-11150___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/12:10126972
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - releaseplasma extra; permeability; encephalopathy; lipopolysacharide; brain; severe sepsis; humna neutrophils; leukocyte adherence; plasma extravasation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Černý, Vladimír
- Lehmann, Christian
- Pavlovic, Dragan
- Wendt, Michael
- Zhou, Juan
- Friedel, Claudius
- Hung, Orlando
- Schroeder, Henry
- Shukla, Romesh
- Whynot, Sara
- Willecke, Julia
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.mvr.2012.03.003
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http://localhost/t...ganizacniJednotka
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