About: Point and Interval Estimates of IC50

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this paper we show how to calculate the point estimation of the IC50 value as well as an appropriate IC50 interval estimation. From the point of view of data treatment, this paper represents a sharp, innovative approach based on precise mathematical interpretation of biophysical relations. The relations derived can initiate the creation of new software products of higher quality. One slight inaccuracy of this paper might be the fact that error uncertainties, in general, (concerning IC50 determining) may not always have normal probability distribution. Naturally, it is possible to demur against it (according to central limit theorem) that every continuous probability distribution asymptotically comes near to normal probability distribution. In this paper we show how to calculate the point estimation of the IC50 value as well as an appropriate IC50 interval estimation. From the point of view of data treatment, this paper represents a sharp, innovative approach based on precise mathematical interpretation of biophysical relations. The relations derived can initiate the creation of new software products of higher quality. One slight inaccuracy of this paper might be the fact that error uncertainties, in general, (concerning IC50 determining) may not always have normal probability distribution. Naturally, it is possible to demur against it (according to central limit theorem) that every continuous probability distribution asymptotically comes near to normal probability distribution. (en)
Title	Point and Interval Estimates of IC50 Point and Interval Estimates of IC50 (en)
skos:prefLabel	Point and Interval Estimates of IC50 Point and Interval Estimates of IC50 (en)
skos:notation	RIV/00216208:11150/11:10109598!RIV12-MSM-11150___
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	F11
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Seifrtová, Martina Řezáčová, Martina Tomšík, Pavel Mičuda, Stanislav Knížek, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	220961
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/11:10109598
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Applied statistics; Software creation; Interval estimate of IC50; Point estimate of IC50; Biochemistry; Inhibitory concentration (en)
http://linked.open.../riv/klicoveSlovo	Biochemistry Applied statistics Inhibitory concentration Interval estimate of IC50 Point estimate of IC50 Software creation
http://linked.open...odStatuVydavatele	IN - Indická republika
http://linked.open...ontrolniKodProRIV	[B02D086C5BFB]
http://linked.open...i/riv/nazevZdroje	International Journal of Tomography and Statistics
http://linked.open...in/vavai/riv/obor	BB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Mičuda, Stanislav Tomšík, Pavel Řezáčová, Martina Seifrtová, Martina Beránek, Ladislav Knížek, Jiří
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	0972-9976
number of pages	29 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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