About: Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ataxia-telangiectasia mutated kinase (ATM) is a DNA damage-inducible protein kinase, which phosphorylates plethora of substrates participating in DNA damage response. ATM significance for the cell faith is undeniable, since it regulates DNA repair, cell-cycle progress, and apoptosis. Here we describe its main signalling targets and discuss its importance in DNA repair as well as novel findings linked to this key regulatory enzyme in the terms of ionizing radiationinduced DNA damage. Ataxia-telangiectasia mutated kinase (ATM) is a DNA damage-inducible protein kinase, which phosphorylates plethora of substrates participating in DNA damage response. ATM significance for the cell faith is undeniable, since it regulates DNA repair, cell-cycle progress, and apoptosis. Here we describe its main signalling targets and discuss its importance in DNA repair as well as novel findings linked to this key regulatory enzyme in the terms of ionizing radiationinduced DNA damage. (en)
Title	Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response (en)
skos:prefLabel	Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response (en)
skos:notation	RIV/00216208:11150/10:10081132!RIV11-MO0-11150___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OVUOFVZ200806), Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Řezáčová, Martina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	248007
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/10:10081132
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA repair; Ionising radiation; p53; ATM (en)
http://linked.open.../riv/klicoveSlovo	p53 Ionising radiation ATM DNA repair
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[EEE83545876B]
http://linked.open...i/riv/nazevZdroje	Acta medica (Hradec Kralove) / Universitas Carolina, Facultas Medica Hradec Kralove
http://linked.open...in/vavai/riv/obor	KA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Noninvasive measurement of proinflamatory markers of oxidative stress in irradiated as an indicator of received dose of radiation. Protective role of acetyl-L-carnitine
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Pejchal, Jaroslav Tichý, Aleš Vávrová, Jiřina Řezáčová, Martina
http://linked.open...n/vavai/riv/zamer	Zdravotnická problematika ZHN
issn	1211-4286
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software