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  • Physiologically based modelling of pharmacodynamics/toxicodynamics requires an a priori knowledge on the underlying mechanisms causing toxicity or causing the disease.In the context of cancer, the objective of expert meeting was to discuss the molecular understanding of the disease, modelling approaches used so far to describe the process, preclinical models of cancer treatment and to evaluate modelling approaches developed based on improved knowledge.
  • Physiologically based modelling of pharmacodynamics/toxicodynamics requires an a priori knowledge on the underlying mechanisms causing toxicity or causing the disease.In the context of cancer, the objective of expert meeting was to discuss the molecular understanding of the disease, modelling approaches used so far to describe the process, preclinical models of cancer treatment and to evaluate modelling approaches developed based on improved knowledge. (en)
Title
  • Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics
  • Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics (en)
skos:prefLabel
  • Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics
  • Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics (en)
skos:notation
  • RIV/00216208:11150/10:10051676!RIV11-MSM-11150___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(OC09071)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 272002
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/10:10051676
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • preclinical models; intracellular pharmacokinetics-pharmacodynamics; molecular mechanisms; physiologically based models; cancer therapeutics; cancerogenesis; physiologically based modelling; pharmacodynamics; pharmacokinetics (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [0D0988F7F0B4]
http://linked.open...i/riv/nazevZdroje
  • European Journal of Cancer
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 46
http://linked.open...iv/tvurceVysledku
  • Martínková, Jiřina
  • Aarons, Leon
  • Ahr, Hans-Jurgen
  • Clairambault, Jean
  • Dahl, Svein G.
  • De Alwis, Dinesh
  • De Nicolao, Giuseppe
  • Freyer, Gilles
  • Friberg, Lena E
  • Gundert-Remy, Ursula
  • Karlsson, Mats O.
  • Kern, Steven E.
  • Kopp-Schneider, Annette
  • Ludwig, Wolf-Dieter
  • Rocchetti, Maurizio
  • Steimer, Jean-Luis
  • Troconiz, Iňaki F.
http://linked.open...ain/vavai/riv/wos
  • 000274103600006
issn
  • 0959-8049
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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