About: Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients

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About: Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Vitamin D plays an absolute essential role in human physiology. In general, VDR activation inhibits cell differentiation and proliferation while promoting cell maturation and it also participates in the regulation of apoptosis. Calcidiol values between 30-60 ng/ml (70-150 nmol/l) are optimal. Low vitamin D status is associated with many pathological conditions. Studies have described association with susceptibility to some infections; higher risk of autoimmune diseases, association with some malignancies and many other complications. In advanced CKD patients, several recent observational studies demonstrated survival benefits of selective VDR activation. These drugs may, at least, partly cover the need for the systemic activation of VDR in kidney patients. Vitamin D plays an absolute essential role in human physiology. In general, VDR activation inhibits cell differentiation and proliferation while promoting cell maturation and it also participates in the regulation of apoptosis. Calcidiol values between 30-60 ng/ml (70-150 nmol/l) are optimal. Low vitamin D status is associated with many pathological conditions. Studies have described association with susceptibility to some infections; higher risk of autoimmune diseases, association with some malignancies and many other complications. In advanced CKD patients, several recent observational studies demonstrated survival benefits of selective VDR activation. These drugs may, at least, partly cover the need for the systemic activation of VDR in kidney patients. (en)
Title	Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients (en)
skos:prefLabel	Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients (en)
skos:notation	RIV/00216208:11150/09:00208729!RIV10-MSM-11150___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021620819)
http://linked.open...iv/cisloPeriodika	Suppl. 1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Dusilová - Sulková, Sylvie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	349011
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/09:00208729
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Calcitriol; Chronic kidney disease; Paricalcitol; Selective vitamin D receptor activation; Syndrome of vitamin D deficiency; Vitamin D; Vitamin D receptor (en)
http://linked.open.../riv/klicoveSlovo	Chronic kidney disease Calcitriol Paricalcitol Selective vitamin D receptor activation Syndrome of vitamin D deficiency Vitamin D Vitamin D receptor
http://linked.open...odStatuVydavatele	FR - Francouzská republika
http://linked.open...ontrolniKodProRIV	[9B6C8C860FBB]
http://linked.open...i/riv/nazevZdroje	Journal of Renal Care
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	35
http://linked.open...iv/tvurceVysledku	Dusilová-Sulková, Sylvie
http://linked.open...n/vavai/riv/zamer	Náhrada a podpora funkce některých životně důležitých orgánů
issn	1755-6678
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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