About: Failure of therapy or resistance to antiplatelet drugs?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Failure of therapy or resistance to antiplatelet drugs? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Even though the efficacy of acetylsalicylic acid (ASA) and clopidogrel has been documented in patients with acute and chronic coronary artery disease (CAD),many patients develop thrombotic cardiovascular complications despite dual antiplatelet therapy due to nonresponsiveness or partial responsiveness. The phenomenon of resistance to antiplatelet therapy remains incompletely defined, influenced as it is by a variety of genetic, cellular, and clinical factors. In conclusion, although clinical guidelines still do not support routine screening for antiplatelet drug resistance (because a standard laboratory assay is still lacking), there is mounting evidence for the need to correlate the laboratory and clinical parameters of platelet activity assessment in different clinical scenarious. Even though the efficacy of acetylsalicylic acid (ASA) and clopidogrel has been documented in patients with acute and chronic coronary artery disease (CAD),many patients develop thrombotic cardiovascular complications despite dual antiplatelet therapy due to nonresponsiveness or partial responsiveness. The phenomenon of resistance to antiplatelet therapy remains incompletely defined, influenced as it is by a variety of genetic, cellular, and clinical factors. In conclusion, although clinical guidelines still do not support routine screening for antiplatelet drug resistance (because a standard laboratory assay is still lacking), there is mounting evidence for the need to correlate the laboratory and clinical parameters of platelet activity assessment in different clinical scenarious. (en)
Title	Failure of therapy or resistance to antiplatelet drugs? Failure of therapy or resistance to antiplatelet drugs? (en)
skos:prefLabel	Failure of therapy or resistance to antiplatelet drugs? Failure of therapy or resistance to antiplatelet drugs? (en)
skos:notation	RIV/00216208:11150/09:00208673!RIV10-MZ0-11150___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR9174)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Pudil, Radek Bis, Josef Vojáček, Jan Malý, Jaroslav Šťásek, Josef Ševčík, Róbert Ševčíková, Hana Dulíček, Petr Fátorová, Ilona
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	314580
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/09:00208673
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Acetylsalicylic acid; Clopidogrel; 'nonresponsineves'; screening; aggregometry (en)
http://linked.open.../riv/klicoveSlovo	Clopidogrel screening aggregometry Acetylsalicylic acid 'nonresponsineves'
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[8D5201869F2B]
http://linked.open...i/riv/nazevZdroje	Cor et Vasa
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	9 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Determination and significance of resistance to antiplatelet therapy
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	51
http://linked.open...iv/tvurceVysledku	Malý, Jaroslav Pecka, Miroslav Pudil, Radek Vojáček, Jan Bis, Josef Šťásek, Josef Ševčík, Róbert Ševčíková, Hana Dulíček, Petr Fátorová, Ilona
issn	0010-8650
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software