About: Aspects of amino acid metabolism in abdominal compartment syndrome

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Increased intra-abdominal pressure is a common finding in intensive care units that may lead to organ dysfunction with severe clinical consequences. We examined the effects of intra-abdominal hypertension on amino acid metabolism. Intra-abdominal hypertension (26 mmHg) was created in male pigs (40-50 kg, n=8) by instillation of saline into the peritoneal cavity. Blood was sampled from the femoral artery and portal vein after 1 hour of resting state, 3 hours of intra-abdominal hypertension and 2 hours after decompression. Amino acid concentrations were measured by high-performance liquid chromatography.The arteriovenous differences indicated the uptake of glutamine, glutamate, serine and ornithine, and release of citrulline by the intestine. Intra-abdominal hypertension resulted in an increase in plasma concentrations of branched-chain amino acids, lysine, phenylalanine, tyrosine, and histidine. Increased intra-abdominal pressure is a common finding in intensive care units that may lead to organ dysfunction with severe clinical consequences. We examined the effects of intra-abdominal hypertension on amino acid metabolism. Intra-abdominal hypertension (26 mmHg) was created in male pigs (40-50 kg, n=8) by instillation of saline into the peritoneal cavity. Blood was sampled from the femoral artery and portal vein after 1 hour of resting state, 3 hours of intra-abdominal hypertension and 2 hours after decompression. Amino acid concentrations were measured by high-performance liquid chromatography.The arteriovenous differences indicated the uptake of glutamine, glutamate, serine and ornithine, and release of citrulline by the intestine. Intra-abdominal hypertension resulted in an increase in plasma concentrations of branched-chain amino acids, lysine, phenylalanine, tyrosine, and histidine. (en)
Title	Aspects of amino acid metabolism in abdominal compartment syndrome Aspects of amino acid metabolism in abdominal compartment syndrome (en)
skos:prefLabel	Aspects of amino acid metabolism in abdominal compartment syndrome Aspects of amino acid metabolism in abdominal compartment syndrome (en)
skos:notation	RIV/00216208:11150/09:00208534!RIV10-MSM-11150___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Holeček, Milan Šišpera, Luděk Sobotka, Luboš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	304127
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/09:00208534
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	abdominal compartment syndrome; amino acids; intestinal ischemia; abdominal hypertension (en)
http://linked.open.../riv/klicoveSlovo	intestinal ischemia abdominal compartment syndrome abdominal hypertension amino acids
http://linked.open...odStatuVydavatele	IT - Italská republika
http://linked.open...ontrolniKodProRIV	[73377ABD5161]
http://linked.open...i/riv/nazevZdroje	Nutritional Therapy and Metabolism
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	27
http://linked.open...iv/tvurceVysledku	Holeček, Milan Sobotka, Luboš Šišpera, Luděk Šafránek, Roman Dobeš, Daniel
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	1828-6232
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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