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| Description
| - Studie negativní komponenty ERP vyvolané změnou v sérii uniformních zvukových podnětů je známa jako mismatch negativita (MMN). U pacientů se schizofrenií je její generování deficitní. Tento deficit je spojen se zhoršeným každodenním fungováním a může být interpretován jako marker progrese schizofrenního onemocnění. MMN vyvolaná zrakovými podněty (vMMN) byla popsána několika výzkumnými týmy, ale u pacientů se schizofrenií dosud studována nebyla. Použitím pohybových stimulací jsme vyvolali zrakovou MMN u 24 pacientů se schizofrenií. Skupinu pacientů jsem porovnali se skupinou zdravých kontrol. U skupiny nemocných byla zjištěna statisticky významně menší vMMN. V dalších analýzách byl zjištěn vztah mezi deficitní vMMN a vyšší dávkou medikace, nižší úrovní fungování a přítomností deficitního syndromu. (cs)
- Studies of an ERP negative amplitude deflection elicited by a change in a series of auditory stimuli is known as mismatch negativity (MMN). The generation of MMN is impaired in schizophrenia. Its deficit is associated with lower everyday functioning and may be also interpreted as the marker of progression in schizophrenia. MMN elicited by visual stimuli (vMMN) was described by several research teams, but it has not been investigated in schizophrenia as yet. Using a motion-direction paradigm, we elicited visual MMN in 24 patients with schizophrenia and schizoaffective disorder. They were compared between groups of patients with schizophrenia and healthy controls. The significantly smaller vMMN indicated an impaired generation of MMN in patients with schizophrenia. In secondary analyses there was an association of vMMN impairment among patients with higher dose of medication, lower level of functioning and the presence of deficit syndrome.
- Studies of an ERP negative amplitude deflection elicited by a change in a series of auditory stimuli is known as mismatch negativity (MMN). The generation of MMN is impaired in schizophrenia. Its deficit is associated with lower everyday functioning and may be also interpreted as the marker of progression in schizophrenia. MMN elicited by visual stimuli (vMMN) was described by several research teams, but it has not been investigated in schizophrenia as yet. Using a motion-direction paradigm, we elicited visual MMN in 24 patients with schizophrenia and schizoaffective disorder. They were compared between groups of patients with schizophrenia and healthy controls. The significantly smaller vMMN indicated an impaired generation of MMN in patients with schizophrenia. In secondary analyses there was an association of vMMN impairment among patients with higher dose of medication, lower level of functioning and the presence of deficit syndrome. (en)
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| Title
| - Visual mismatch negativity in deficit and nondeficit schizophrenia
- Zraková mismatch negativita u pacientů se schizofrenií (cs)
- Visual mismatch negativity in deficit and nondeficit schizophrenia (en)
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| skos:prefLabel
| - Visual mismatch negativity in deficit and nondeficit schizophrenia
- Zraková mismatch negativita u pacientů se schizofrenií (cs)
- Visual mismatch negativity in deficit and nondeficit schizophrenia (en)
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| skos:notation
| - RIV/00216208:11150/08:00106989!RIV09-MSM-11150___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/08:00106989
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - schizophrenia; event related potentials; mismatch negativity; visual mismatch negativity; information processing (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/mistoVydani
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Kremláček, Jan
- Kuba, Miroslav
- Libiger, Jan
- Masopust, Jiří
- Urban, Aleš
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| http://linked.open...n/vavai/riv/zamer
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| number of pages
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| http://purl.org/ne...btex#hasPublisher
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| https://schema.org/isbn
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| http://localhost/t...ganizacniJednotka
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