About: Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging

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About: Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The pathophysiology of microcirculation is intensively investigated to understand disease development at the microscopic level. The goal of this experimental study was to describe basic microcirculatory parameters of skeletal muscle and ileal serous surface microcirculation in the rat using SDF imaging and to standardize the technical aspects of the protocol. There was no statistically significant difference in mean values of FCD obtained from the muscle (P = 0.273) in contrast to ileal serous surface where the difference was statistically significant (P = 0.036). Neither on the muscle surface (P = 0.739) nor on ileal serous surface (P = 0.659) statistically significant differences in small vessels percentage was detected. Our study has shown that SDF imaging represents promising technology for experimental and clinical studies. The pathophysiology of microcirculation is intensively investigated to understand disease development at the microscopic level. The goal of this experimental study was to describe basic microcirculatory parameters of skeletal muscle and ileal serous surface microcirculation in the rat using SDF imaging and to standardize the technical aspects of the protocol. There was no statistically significant difference in mean values of FCD obtained from the muscle (P = 0.273) in contrast to ileal serous surface where the difference was statistically significant (P = 0.036). Neither on the muscle surface (P = 0.739) nor on ileal serous surface (P = 0.659) statistically significant differences in small vessels percentage was detected. Our study has shown that SDF imaging represents promising technology for experimental and clinical studies. (en) Experimentální práce zamřená na vyhodnocení mikrocirkulace kosterního svalu a střevní stěny potkana metodou Sidestream dark-field (SDF) imaging s důrazem na standardizaci metodiky a porovnání výsledků s dostupnými daty z validačních studií. Nebyl zjištěn statisticky významný interindividuální rozdíl v hodnotách FCD kosterního svalu na rozdíl od hodnot FCD střevní stěny, kde byl zjištěn rozdíl na hranici statistické významnosti. Studie dokumentuje možnost využití SDF technologie jako spolehlivé metody při zobrazování změn mikrocirkulace s velkým potenciálem využití v experimentu i klinické praxi. (cs)
Title	Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging (en) Posouzení mikrocirkulace svalu a střeva u potkana (cs)
skos:prefLabel	Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging (en) Posouzení mikrocirkulace svalu a střeva u potkana (cs)
skos:notation	RIV/00216208:11150/08:00106758!RIV09-MZ0-11150___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Černý, Vladimír Pařízková, Renata
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	382845
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/08:00106758
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	SDF imaging; microcirculation; functional capillary density; ileum; skeletal muscle (en)
http://linked.open.../riv/klicoveSlovo	ileum microcirculation SDF imaging skeletal muscle functional capillary density
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[F6769AE219BC]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	57
http://linked.open...iv/tvurceVysledku	Pařízková, Renata Černý, Vladimír Turek, Zdeněk
http://linked.open...ain/vavai/riv/wos	000257270900006
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0862-8408
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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