About: The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis

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About: The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The prospective study examined the influence of folic acid (20 mg/week) on the pharmacokinetics of oral methotrexate and its therapeutic effect in patients with plaque psoriasis (PASI score) and toxicity. The prospective study examined the influence of folic acid (20 mg/week) on the pharmacokinetics of oral methotrexate and its therapeutic effect in patients with plaque psoriasis (PASI score) and toxicity. (en) Prospektivní klinická studie hodnotila vliv farmakologické suplementace kyselinou listovou na farmakokinetiku perorálního metotrexátu a jeho účinek (skóre PASI) a nežádoucí účinky u nemocných s psoriázou.ntal period - a risk group for the development of non-compliance. Similarly to other age groups, in chronic diseases the periods at risk are especially those without symptoms. The article outlines a survey of forms and factors on n (cs)
Title	The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis (en) Vliv suplementace kyselinou listovou na farmakokinetiku a farmakodynamiku perorálního metotrexátu ve fázi indukce remise psoriázy (cs)
skos:prefLabel	The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis (en) Vliv suplementace kyselinou listovou na farmakokinetiku a farmakodynamiku perorálního metotrexátu ve fázi indukce remise psoriázy (cs)
skos:notation	RIV/00216208:11150/08:00106752!RIV09-MZ0-11150___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1P05OC066), P(NR7947), Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Beránek, Martin Hroch, Miloš Chládek, Jaroslav Chládková, Jiřina Martínková, Jiřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	365090
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/08:00106752
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	methotrexate; folic acid; psoriasis; psoriasis area and severity index (en)
http://linked.open.../riv/klicoveSlovo	folic acid psoriasis methotrexate psoriasis area and severity index
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[E57ED0EA4F47]
http://linked.open...i/riv/nazevZdroje	European Journal of Clinical Pharmacology
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Physiologically based modelling of nitric oxide disposition and effects in airways disease New approaches to evaluation and prevention of toxicity of long-term pharmacotherapy of psoriasis with methotrexate: pharmacokinetics and influences of the genetic polymorphism of methylenetetrahydrofolate reductase and folate supplementation.
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	64
http://linked.open...iv/tvurceVysledku	Beránek, Martin Chládek, Jaroslav Chládková, Jiřina Vaněčková, Jaroslava Hroch, Miloš Vávrová, Jaroslava Martínková, Jiřina Šimková, Marie
http://linked.open...ain/vavai/riv/wos	000253571000004
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	0031-6970
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

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