About: The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli     Goto   Sponge   NotDistinct   Permalink

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  • The aim of this study was to obtain topographical information about Land M-cone activity at the ganglion cell layer using multifocal pattern electroretinography (mfPERG). A standard (black and white) stimulus was used, as well as stimuli modulating only the long wavelength-sensitive (L) or only the middle wavelength-sensitive (M) cones. The L:M ratio was calculated from the amplitude of the L-cone isolating mfPERG to that of the M-cone isolating mfPERG of 10 trichromats. Both the positive and negative components of the waveform were analyzed. Additional recordings of single cone modulated mfERGs were obtained from nine of the 10 subjects. We also recorded from one protanope and one deuteranope. The L:M cone amplitude ratios for both deflections of the mfPERG in the trichromats were around unity (medians 1.18 and 1.16, respectively) for the central 8° of retina. In the peripheral retina between 12.8° and 26°, this ratio increased to 1.42 for the positive component, and 1.37 for the negative component.
  • The aim of this study was to obtain topographical information about Land M-cone activity at the ganglion cell layer using multifocal pattern electroretinography (mfPERG). A standard (black and white) stimulus was used, as well as stimuli modulating only the long wavelength-sensitive (L) or only the middle wavelength-sensitive (M) cones. The L:M ratio was calculated from the amplitude of the L-cone isolating mfPERG to that of the M-cone isolating mfPERG of 10 trichromats. Both the positive and negative components of the waveform were analyzed. Additional recordings of single cone modulated mfERGs were obtained from nine of the 10 subjects. We also recorded from one protanope and one deuteranope. The L:M cone amplitude ratios for both deflections of the mfPERG in the trichromats were around unity (medians 1.18 and 1.16, respectively) for the central 8° of retina. In the peripheral retina between 12.8° and 26°, this ratio increased to 1.42 for the positive component, and 1.37 for the negative component. (en)
  • Cílem této studie bylo získat topografickou informaci o aktivitě L a M čípků v buněčné ganglionové vrstvě pomocí elektroretinografie multifokálního uspořádání (mfERG). Byl použit standardní černý a bílý stimulus stejně tak jako stimuly modulující L a M čípky. Poměr mezi L a M byl vypočítán z amplitudy L-čípku izolujícího mfERG a M-čípku izolujícího mfERG 10 trichromátů. Také jsme analyzovali údaje od 1 protanopa a 1 deuteranopa . Poměr mezi La M amplitudami byly jednotné pro centrální 8°sítnice. Na periferii sítnice mezi 12,8°a 26°byl tento poměr zvýšený na 1,42 pro pozitivní část a 1,37 pro negativní část. Střední hodnoty L:M amplitudových poměrů pro mfERG byly vyšší a pohybovaly se v rozmezí 1,00-2,78 na periferii. Tyto výsledky naznačují, že hlavní přizpůsobení zesílení sítnicových signálů se vyskytuje v buněčné ganglionové vrstvě a že poměr je vyšší na periferii než ve střední části sítnice. (cs)
Title
  • The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli
  • Barevný multifokální elektroretinogram na reverzační podnět (mfPERG). (cs)
  • The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli (en)
skos:prefLabel
  • The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli
  • Barevný multifokální elektroretinogram na reverzační podnět (mfPERG). (cs)
  • The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli (en)
skos:notation
  • RIV/00216208:11150/07:00004215!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany
  • 805;816
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  • 435615
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  • RIV/00216208:11150/07:00004215
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  • multifocal; pattern; electroretinogram; mfPERG; cone-isolating; stimuli (en)
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  • US - Spojené státy americké
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  • [BCF52A469689]
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  • Visual Neuroscience
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  • 24
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  • Langrová, Hana
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  • 0952-5238
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  • 11150
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