About: Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this work, it was revealed that valid and routine determination of left-ventricular filling pattern in rabbit is hindered by relatively high physiological heart rate and therefore, it was shown to be unsuitable for early determination of anthracycline cardiotoxicity on this model. On the other hand, troponin T determination was demonstrated as very sensitive and earliest marker of cardiotoxicity on our model preceding all functional changes. In this work, it was revealed that valid and routine determination of left-ventricular filling pattern in rabbit is hindered by relatively high physiological heart rate and therefore, it was shown to be unsuitable for early determination of anthracycline cardiotoxicity on this model. On the other hand, troponin T determination was demonstrated as very sensitive and earliest marker of cardiotoxicity on our model preceding all functional changes. (en) V této práci bylo zjištěno, že validní a rutinní hodnocení plnění levé komory u králíka je relativně obtížné s ohledem na relativně vysokou fyziologickou frekvenci, a proto se ukázal nevhodný pro časný záchyt antracyklinové kardiotoxicity na tomto modelu. Na druhou stranu, bylo demonstrováno, že troponin T je citlivým a nejčasnějším markerem antracyklinové kardiotoxicity, který předchází změnám funkce levé komory. (cs)
Title	Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination (en) Časná detekce antracyklinové kardiotoxicity na modelu králíka: parametry plnění levé komory versus stanovení troponinu T (cs)
skos:prefLabel	Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination (en) Časná detekce antracyklinové kardiotoxicity na modelu králíka: parametry plnění levé komory versus stanovení troponinu T (cs)
skos:notation	RIV/00216208:11150/07:00003698!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany	535;545
http://linked.open...avai/riv/aktivita	V Z
http://linked.open...avai/riv/aktivity	V, Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Mazurová, Yvona Geršl, Vladimír Štěrba, Martin Popelová, Olga Potáčová, Anna Adamcová, Michaela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	418566
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/07:00003698
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	daunorubicin; anthracycline; cardiotoxicity; early detection; diastolic dysfunction; cardiac troponin T (en)
http://linked.open.../riv/klicoveSlovo	daunorubicin diastolic dysfunction cardiac troponin T anthracycline cardiotoxicity early detection
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[D94E9F9E8761]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	56
http://linked.open...iv/tvurceVysledku	Adamcová, Michaela Geršl, Vladimír Popelová, Olga Štěrba, Martin Mazurová, Yvona Potáčová, Anna
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	0862-8408
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	11150

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software